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Michelle T. Ma

Researcher at St Thomas' Hospital

Publications -  63
Citations -  1552

Michelle T. Ma is an academic researcher from St Thomas' Hospital. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 18, co-authored 48 publications receiving 1239 citations. Previous affiliations of Michelle T. Ma include University of Melbourne & Monash University, Clayton campus.

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Comparison of (64)Cu-complexing bifunctional chelators for radioimmunoconjugation: labeling efficiency, specific activity, and in vitro/in vivo stability.

TL;DR: While all the macrocyclic bifunctional chelators are suitable for molecular imaging using (64)Cu-labeled antibody conjugates, NOTA and sar-CO2H show significant advantages over the others in that they can be radiolabeled rapidly at room temperature, under dilute conditions, resulting in high specific activity.
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Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling

TL;DR: A range of macrocyclic and acyclic chelators have been reacted with the PET isotope, gallium-68, and their radiolabelling efficiencies have been compared and structural data for complexes of HBED with Ga3+ are reported.
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68Ga-THP-PSMA: A PET Imaging Agent for Prostate Cancer Offering Rapid, Room-Temperature, 1-Step Kit-Based Radiolabeling.

TL;DR: The aim of this study was to develop and evaluate preclinically a 68Ga radiotracer for imaging PSMA expression that could be radiolabeled simply by addition of 68Ga generator eluate to a cold kit, and THP offers the prospect of rapid, simple, 1-step, room-temperature syringe-and-vial Radiolabeling of 68 Ga radiopharmaceuticals.