M
Michihisa Jougasaki
Researcher at Mayo Clinic
Publications - 96
Citations - 10765
Michihisa Jougasaki is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Natriuretic peptide & Brain natriuretic peptide. The author has an hindex of 45, co-authored 96 publications receiving 10528 citations. Previous affiliations of Michihisa Jougasaki include Kyoto University & Kumamoto University.
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Journal ArticleDOI
Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.
Masashi Mukoyama,Kazumasa Nakao,Kiminori Hosoda,Shin Ichi Suga,Yoshihiko Saito,Yoshihiro Ogawa,Gotaro Shirakami,Michihisa Jougasaki,K Obata,Hirofumi Yasue +9 more
TL;DR: Results indicate that BNP is a novel cardiac hormone secreted predominantly from the ventricle, and that the synthesis, secretion and clearance of BNP differ from those of ANP, suggesting discrete physiological and pathophysiological roles of HBNP in a dual natriuretic peptide system.
Journal ArticleDOI
Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure.
Hirofumi Yasue,Michihiro Yoshimura,Hitoshi Sumida,Koichi Kikuta,Kiyotaka Kugiyama,Michihisa Jougasaki,Hisao Ogawa,Ken Okumura,Masashi Mukoyama,Kazuwa Nakao +9 more
TL;DR: Examination of the sources and mechanisms of the secretion of BNP in comparison with those of ANP in control subjects and in patients with heart failure concludes that BNP is secreted mainly from the left ventricle in normal adult humans as well as in Patients with left ventricular dysfunction.
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Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure.
Michihiro Yoshimura,Hirofumi Yasue,Ken Okumura,Hisao Ogawa,Michihisa Jougasaki,Masashi Mukoyama,Kazuwa Nakao,Hiroo Imura +7 more
TL;DR: It is concluded that plasma levels of BNP mainly reflect the degree of ventricular overload and that the secretion patterns of ANP and BNP vary with underlying cardiac disorders of CHF with different degrees of overload in atria and ventricles.
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Increased plasma levels of brain natriuretic peptide in patients with acute myocardial infarction.
Etsuo Morita,Hirofumi Yasue,Michihiro Yoshimura,Hisao Ogawa,Michihisa Jougasaki,Toshiyuki Matsumura,Masashi Mukoyama,Kazuwa Nakao +7 more
TL;DR: It is concluded that the plasma level of brain natriuretic peptide is increased markedly in patients with acute myocardial infarction and may reflect the degree of left ventricular dysfunction in these patients.
Journal ArticleDOI
Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy.
Kazuhiro Yamamoto,John C. Burnett,Michihisa Jougasaki,Rick A. Nishimura,Kent R. Bailey,Yoshihiko Saito,Kazuwa Nakao,Margaret M. Redfield +7 more
TL;DR: An elevated plasma BNP was a more powerful marker ofleft ventricular systolic dysfunction, left ventricular diastolic function and left vent cardiac hypertrophy than C-terminal ANP or N-terminAL ANP-(1-30) in this population of patients with suspected cardiac disease.