M
Miguel A. Ondetti
Researcher at Princeton University
Publications - 160
Citations - 8019
Miguel A. Ondetti is an academic researcher from Princeton University. The author has contributed to research in topics: Angiotensin-converting enzyme & Alkyl. The author has an hindex of 35, co-authored 160 publications receiving 7886 citations. Previous affiliations of Miguel A. Ondetti include IBM.
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Synthesis of secretin. II. The stepwise approach.
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Synthesis of cholecystokinin-pancreozymin. I. The C-terminal dodecapeptide.
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Design of new antihypertensive drugs: Potent and specific inhibitors of angiotensin-converting enzyme
TL;DR: A hypothetical model of the mechanism of binding of substrates to its active site of angiotensin-converting enzyme is developed and more potent inhibitors of the enzyme that were shown to be orally active in rats are synthesized.
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Inhibition of angiotensin-coverting enzyme by analogs of peptides from Bothrops jararaca venom.
David W. Cushman,Josip Pluscec,N. J. Williams,E R Weaver,E. F. Sabo,Kocy O,H S Cheung,Miguel A. Ondetti +7 more
TL;DR: In this paper, weis mit Analogen der im Gifte vonBothrops jararaca gefundenen Peptide, dass die Inhihibition des Angiotensins "converting enzyme" von zwei eindeutigen Teilsequenzen dieser Peptides abhangig ist.