Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound.
Ik-Kyung Jang,Brett E. Bouma,Dong-Heon Kang,Dong-Heon Kang,Seung-Jung Park,Seong-Wook Park,Ki-Bae Seung,Kyu-Bo Choi,Milen Shishkov,Kelly Schlendorf,Eugene Pomerantsev,Stuart L. Houser,H. Thomas Aretz,Guillermo J. Tearney +13 more
TLDR
Comparison between OCT and histology demonstrated that lipid-rich plaques and fibrous plaques have distinct OCT characteristics, and intracoronary OCT appears to be feasible and safe.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2002-02-20 and is currently open access. It has received 1094 citations till now. The article focuses on the topics: Fibrous cap & Intravascular ultrasound.read more
Citations
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From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.
Morteza Naghavi,Peter Libby,Erling Falk,S. Ward Casscells,S. Ward Casscells,Silvio H. Litovsky,Silvio H. Litovsky,John A. Rumberger,Juan J. Badimon,Christodoulos Stefanadis,Pedro R. Moreno,Gerard Pasterkamp,Zahi A. Fayad,Peter Stone,Sergio Waxman,Paolo Raggi,Mohammad Madjid,Mohammad Madjid,Alireza Zarrabi,Alireza Zarrabi,Allen P. Burke,Chun Yuan,Peter J. Fitzgerald,David S. Siscovick,Chris L. de Korte,Masanori Aikawa,K.E. Juhani Airaksinen,Gerd Assmann,Christoph R. Becker,James H. Chesebro,Andrew Farb,Zorina S. Galis,Christopher L. Jackson,Ik-Kyung Jang,Wolfgang Koenig,Robert A. Lodder,Keith L. March,Jasenka Demirovic,Mohamad Navab,Silvia G. Priori,Mark D. Rekhter,Raymond D. Bahr,Scott M. Grundy,Roxana Mehran,Antonio Colombo,Eric Boerwinkle,Christie M. Ballantyne,William Insull,Robert S. Schwartz,Robert A. Vogel,Patrick W. Serruys,Göran K. Hansson,David P. Faxon,Sanjay Kaul,Helmut Drexler,Philip Greenland,James E. Muller,Renu Virmani,Renu Virmani,Paul M. Ridker,Douglas P. Zipes,Prediman K. Shah,James T. Willerson,James T. Willerson +63 more
TL;DR: The term "vulnerable patient" may be more appropriate and is proposed now for the identification of subjects with high likelihood of developing cardiac events in the near future and a quantitative method for cumulative risk assessment of vulnerable patients needs to be developed.
Journal ArticleDOI
Imaging and photodynamic therapy: mechanisms, monitoring, and optimization.
Jonathan P. Celli,Bryan Q. Spring,Imran Rizvi,Conor L. Evans,Kimberley S. Samkoe,Sarika Verma,Brian W. Pogue,Tayyaba Hasan +7 more
TL;DR: The basic premise of this review is that a combination of imaging and PDT will provide improved research and therapeutic strategies.
Journal ArticleDOI
Characterization of Human Atherosclerosis by Optical Coherence Tomography
Hiroshi Yabushita,Brett E. Bouma,Stuart L. Houser,H. Thomas Aretz,Ik-Kyung Jang,Kelly Schlendorf,Christopher R. Kauffman,Milen Shishkov,Dong-Heon Kang,Elkan F. Halpern,Guillermo J. Tearney +10 more
TL;DR: Objective OCT criteria are highly sensitive and specific for characterizing different types of atherosclerotic plaques in vitro and will provide a basis for the interpretation of intracoronary OCT images obtained from patients.
Journal ArticleDOI
Biomarkers of cardiovascular disease: molecular basis and practical considerations.
TL;DR: This review provides an overview of the molecular basis of biomarker discovery and selection and the practical considerations that are a prerequisite to their clinical use.
Journal ArticleDOI
Optical coherence tomography for ultrahigh resolution in vivo imaging
TL;DR: Optical coherence tomography functions as a type of 'optical biopsy' to provide cross-sectional images of tissue structure on the micron scale and is a promising imaging technology because it can provide images of tissues in situ and in real time, without the need for excision and processing of specimens.
References
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Lessons From Sudden Coronary Death A Comprehensive Morphological Classification Scheme for Atherosclerotic Lesions
TL;DR: This review will reconsider the current paradigm for understanding the critical, final steps in the progression of atherosclerotic lesions, and devise a simpler classification scheme that is consistent with the AHA categories but is easier to use, able to deal with a wide array of morphological variations, and not overly burdened by mechanistic implications.
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Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi.
TL;DR: A severe chronic stenosis seems to be a prerequisite for occlusive thrombus formation, but the thrombotic process itself is triggered by an acute intimal lesion.
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Catheter-based radiotherapy to inhibit restenosis after coronary stenting
Paul S. Teirstein,Vincent Massullo,Shirish Jani,Jeffrey J. Popma,Gary S. Mintz,Robert J. Russo,Richard A. Schatz,Erminia M. Guarneri,Stephen Steuterman,Nancy B. Morris,Martin B. Leon,Prabhakar Tripuraneni +11 more
TL;DR: In this preliminary, short-term study of patients with previous coronary restenosis, coronary stenting followed by catheter-based intracoronary radiotherapy substantially reduced the rate of subsequent restenotic.
Journal ArticleDOI
Optical Coherence Tomography for Optical Biopsy Properties and Demonstration of Vascular Pathology
Mark E. Brezinski,Guillermo J. Tearney,Brett E. Bouma,Joseph A. Izatt,Michael R. Hee,Eric A. Swanson,James F. Southern,James G. Fujimoto +7 more
TL;DR: OCT represents a promising new technology for imaging vascular microstructure with a level of resolution not previously achieved with the use of other imaging modalities, and can be performed with a catheter integrated with a relatively inexpensive optical fiber.
Journal ArticleDOI
The Unstable Atheroma
Richard T. Lee,Peter Libby +1 more
TL;DR: It is proposed that the basic biology of the unstable lesion will now assume even greater importance for two fundamental reasons: first, even with aspirin and cholesterol-lowering therapy, acute vascular events will continue to be a major cause of morbidity and mortality in developed countries.
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