M
Mincheol Kwon
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 9
Citations - 86
Mincheol Kwon is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Autophagy & Sophora flavescens. The author has an hindex of 4, co-authored 9 publications receiving 47 citations. Previous affiliations of Mincheol Kwon include Korea University of Science and Technology.
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Journal ArticleDOI
Herqueilenone A, a unique rearranged benzoquinone-chromanone from the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729.
Jae Sik Yu,Chun-Shun Li,Mincheol Kwon,Taehoon Oh,Tae Hyun Lee,Dong Hyun Kim,Jong Seog Ahn,Sung-Kyun Ko,Chung Sub Kim,Shugeng Cao,Ki-Hyun Kim +10 more
TL;DR: The study of a Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729 led to the isolation of one unprecedented benzoquinone-chromanone, herqueilenone A and two phenalenone derivatives, whose structures were determined through extensive analysis of NMR spectroscopic data and gauge-including atomic orbital (GIAO) NMR chemical shifts and ECD calculations.
Journal ArticleDOI
Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity.
Mincheol Kwon,Mincheol Kwon,Sung-Kyun Ko,Mina Jang,Mina Jang,Gun-Hee Kim,In-Ja Ryoo,Sangkeun Son,Hyung Won Ryu,Sei-Ryang Oh,Won-Kyu Lee,Bo Yeon Kim,Bo Yeon Kim,Jae-Hyuk Jang,Jae-Hyuk Jang,Jong Seog Ahn,Jong Seog Ahn +16 more
TL;DR: The results suggest that the flavonoids of S. flavescens, especially kushenol E (6), as IDO1 inhibitors might be useful in the development of immunotherapeutic agents against cancers.
Journal ArticleDOI
Ent-Peniciherqueinone Suppresses Acetaldehyde-Induced Cytotoxicity and Oxidative Stress by Inducing ALDH and Suppressing MAPK Signaling.
Taehoon Oh,Taehoon Oh,Mincheol Kwon,Mincheol Kwon,Jae Sik Yu,Mina Jang,Gun-Hee Kim,Ki Hyun Kim,Sung-Kyun Ko,Jong Seog Ahn,Jong Seog Ahn +10 more
TL;DR: Ent-peniciherqueinone isolated from a Hawaiian volcanic soil-associated fungus was found to reduce the acetaldehyde-induced cytotoxicity and oxidative stress and functions as a potent agent to suppress hangover symptoms and alcohol-related stress.
Journal ArticleDOI
Analysis of active metabolites of Sophora flavescens for indoleamine 2,3-dioxygenase and monoamine oxidases using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
Mi Hyeon Park,Seong Mi Lee,Sung-Kyun Ko,Sung-Kyun Ko,Kyeong Yeol Oh,Jung Hee Kim,Hoon Kim,Mincheol Kwon,Mincheol Kwon,In-Ja Ryoo,Jong Seog Ahn,Jong Seog Ahn,Hyung Won Ryu,Sei-Ryang Oh +13 more
TL;DR: As part of ongoing research on natural products derived from medicinal plants for enzyme inhibition, known dibenzoyl derivatives (1−3, 11 and 20), pterocarpans (4, 15 and 19), flavanones (5, 7, 10,...
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Enhanced mating-type switching and sexual hybridization in heterothallic yeast Yarrowia lipolytica.
Changpyo Han,Changpyo Han,Heeun Kwon,Gyuyeon Park,Gyuyeon Park,Minjeong Jang,Hye Jeong Lee,Sung-Hwa Seo,Mincheol Kwon,Mincheol Kwon,Wooyoung Jeon,Heeseok Lee,Heeseok Lee,Hongweon Lee,Hongweon Lee,Jungoh Ahn,Jungoh Ahn +16 more
TL;DR: The goal of this study was to evaluate the effectiveness of a mating-type switching strategy by single step transformation without a genetic manipulation vestige, and to optimize the conventional method for increasing ploidy (mating) in Y. lipolytica.