C
Chung Sub Kim
Researcher at Sungkyunkwan University
Publications - 98
Citations - 1312
Chung Sub Kim is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 16, co-authored 83 publications receiving 835 citations. Previous affiliations of Chung Sub Kim include Yale University.
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Journal ArticleDOI
Structure elucidation of colibactin and its DNA cross-links
Mengzhao Xue,Chung Sub Kim,Alan R. Healy,Kevin M. Wernke,Zhixun Wang,Madeline C. Frischling,Emilee E. Shine,Weiwei Wang,Seth B. Herzon,Jason M. Crawford +9 more
TL;DR: The structure of colibactin is revealed, which accounts for the entire gene cluster encoding its biosynthesis, a goal that has remained beyond reach for more than a decade.
Journal ArticleDOI
Characterization of Autoinducer-3 Structure and Biosynthesis in E. coli.
Chung Sub Kim,Alexandra Gatsios,Santiago Cuesta,Yick Chong Lam,Zheng Wei,Haiwei Chen,Regan M. Russell,Emilee E. Shine,Rurun Wang,Thomas P. Wyche,Grazia Piizzi,Richard A. Flavell,Noah W. Palm,Vanessa Sperandio,Jason M. Crawford +14 more
TL;DR: The structure and biosynthesis of autoinducer-3 (AI-3), a metabolite of previously unknown structure involved in the pathogenesis of enterohemorrhagic E. coli (EHEC), are defined and it is shown that the metabolites exert diverse immunological effects on primary human tissues.
Journal ArticleDOI
A community resource for paired genomic and metabolomic data mining
Michelle Schorn,Stefan Verhoeven,Lars Ridder,Florian Huber,Deepa D. Acharya,Alexander A. Aksenov,Gajender Aleti,Jamshid Amiri Moghaddam,Allegra T. Aron,Saefuddin Aziz,Saefuddin Aziz,Anelize Bauermeister,Anelize Bauermeister,Katherine D. Bauman,Martin Baunach,Christine Beemelmanns,J. Michael Beman,María Victoria Berlanga-Clavero,Alex A. Blacutt,Helge B. Bode,Anne Boullie,Asker Daniel Brejnrod,Tim S. Bugni,Alexandra Calteau,Liu Cao,Víctor J. Carrión,Raquel Castelo-Branco,Raquel Castelo-Branco,Shaurya Chanana,Alexander B. Chase,Marc G. Chevrette,Letícia V. Costa-Lotufo,Jason M. Crawford,Cameron R. Currie,Cameron R. Currie,Bart Cuypers,Bart Cuypers,Tam Dang,Tristan de Rond,Alyssa M. Demko,Elke Dittmann,Chao Du,Christopher Drozd,Jean-Claude Dujardin,Rachel J. Dutton,Anna Edlund,Anna Edlund,David P. Fewer,Neha Garg,Julia M. Gauglitz,Emily C. Gentry,Lena Gerwick,Evgenia Glukhov,Harald Gross,Muriel Gugger,Dulce G. Guillén Matus,Eric J. N. Helfrich,Benjamin-Florian Hempel,Benjamin-Florian Hempel,Jae Seoun Hur,Marianna Iorio,Paul R. Jensen,Kyo Bin Kang,Leonard Kaysser,Neil L. Kelleher,Chung Sub Kim,Chung Sub Kim,Ki-Hyun Kim,Irina Koester,Gabriele M. König,Tiago Leao,Tiago Leao,Seoung Rak Lee,Seoung Rak Lee,Yi Yuan Lee,Xuanji Li,Jessica C. Little,Katherine N. Maloney,Daniel Männle,Christian Martin H,Andrew C. McAvoy,Willam W. Metcalf,Hosein Mohimani,Carlos Molina-Santiago,Bradley S. Moore,Bradley S. Moore,Michael W. Mullowney,Mitchell N. Muskat,Louis-Félix Nothias,Ellis C. O’Neill,Elizabeth I. Parkinson,Daniel Petras,Daniel Petras,Jörn Piel,Emily C Pierce,Karine Pires,Raphael Reher,Diego Romero,M. Caroline Roper,Michael J. Rust,Hamada Saad,Carmen Saenz,Laura M. Sanchez,Søren J. Sørensen,Margherita Sosio,Roderich D. Süssmuth,Douglas Sweeney,Kapil Tahlan,Regan J. Thomson,Nicholas J. Tobias,Amaro E. Trindade-Silva,Gilles P. van Wezel,Mingxun Wang,Kelly C. Weldon,Kelly C. Weldon,Fan Zhang,Nadine Ziemert,Katherine R. Duncan,Max Crüsemann,Simon Rogers,Pieter C. Dorrestein,Marnix H. Medema,Justin J. J. van der Hooft +122 more
TL;DR: The Paired Omics Data Platform as mentioned in this paper is a community initiative to systematically document links between metabolome and (meta)genome data, aiding identification of natural product biosynthetic origins and metabolite structures.
Journal ArticleDOI
ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance
Prabhanshu Tripathi,Emilee E. Shine,Alan R. Healy,Chung Sub Kim,Seth B. Herzon,Steven D. Bruner,Jason M. Crawford +6 more
TL;DR: This study provides a molecular-level view of the first reported cyclopropane hydrolase and support for a specific mechanistic role of this enzyme in colibactin resistance and provides a means for the bacteria to circumvent self-induced genotoxicity.
Journal ArticleDOI
Salicin derivatives from Salix glandulosa and their biological activities
Chung Sub Kim,Lalita Subedi,Kyoung Jin Park,Sun Yeou Kim,Sang Un Choi,Ki-Hyun Kim,Kang Ro Lee +6 more
TL;DR: Results revealed that salicin derivatives from Salix glandulosa might have potent effect as anti-neuroinflammatory agents.