M
Ming Xiang
Researcher at Huazhong University of Science and Technology
Publications - 75
Citations - 1455
Ming Xiang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: T cell & Medicine. The author has an hindex of 20, co-authored 63 publications receiving 1132 citations. Previous affiliations of Ming Xiang include University of Catania & Heidelberg University.
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Journal ArticleDOI
The soybean peptide aglycin regulates glucose homeostasis in type 2 diabetic mice via IR/IRS1 pathway.
Jingli Lu,Ying Zeng,Wen-Rui Hou,Sha-Sha Zhang,Lu-Lu Li,Xiang Luo,Wei Xi,Zhengwang Chen,Ming Xiang +8 more
TL;DR: Oral administration of aglycin can potentially attenuate or prevent hyperglycemia by increasing insulin receptor signaling pathway in the skeletal muscle of streptozotocin/high-fat-diet-induced diabetic mice.
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Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency.
R. Di Marco,Ming Xiang,P. Zaccone,C. Leonardi,Scorziello Franco,Pier Luigi Meroni,Ferdinando Nicoletti +6 more
TL;DR: The results prove the physiological antiinflammatory role of endogenous IL-10 in Con A induced hepatitis and the beneficial effects of IL- 10 treatment to prevent this condition.
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REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: Involvement of a REG3A–JAK2/STAT3 positive feedback loop
TL;DR: It is determined that exposure of human PaC cells to cytokine IL-6 activated the oncogenic JAK2/STAT3 pathway, which directly upregulated REG3A expression, accelerated cell cycle progression by promoting CyclinD1 expression, and enhancing the expression of the anti-apoptosis Bcl family.
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(±)-Acortatarinowins A–F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii
Yuanyuan Lu,Yongbo Xue,Junjun Liu,Guangmin Yao,Dongyan Li,Bin Sun,Jinwen Zhang,Yanfei Liu,Changxing Qi,Ming Xiang,Zengwei Luo,Guang Du,Yonghui Zhang +12 more
TL;DR: Eight pairs of enantiomers 1a/1b-8a/8b, which had variable enantiomeric excess (ee) values of approximately 66, 71, 63, 60, 0, 38, 48, and 75%, respectively, were isolated from the rhizomes of Acorus tatarinowii.
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Dichotomic effects of IFN-γ on the development of systemic lupus erythematosus-like syndrome in MRL-lpr/lpr mice
Ferdinando Nicoletti,Roberto Di Marco,P. Zaccone,Ming Xiang,Gaetano Magro,S. Grasso,Stefania Morrone,Angela Santoni,Yehuda Shoenfeld,Gianni Garotta,Pier Luigi Meroni +10 more
TL;DR: The dichotomic effect of IFN‐γ on disease manifestation in MRL‐lpr mice offers new insights into the complex role of this cytokine in the regulation of systemic autoimmunity such as SLE.