M
Ming-Yang Lai
Researcher at National Taiwan University
Publications - 191
Citations - 10706
Ming-Yang Lai is an academic researcher from National Taiwan University. The author has contributed to research in topics: Hepatitis B virus & Hepatitis B. The author has an hindex of 54, co-authored 191 publications receiving 10498 citations. Previous affiliations of Ming-Yang Lai include Taipei Medical University & Academia Sinica.
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Journal ArticleDOI
Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
TL;DR: The data suggest that HBV genotype C is associated with more severe liver disease and genotype B may be associated with the development of HCC in young Taiwanese, and additional large-scale longitudinal studies are needed to confirm the relationship ofHBV genotypes to liver disease severity and clinical outcomes.
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Hepatitis B genotypes and the response to interferon therapy.
TL;DR: HBV genotype C, compared to genotype B, is associated with a higher frequency of core promoter mutation, and a lower response rate to interferon alfa therapy.
Journal ArticleDOI
Growth rate of asymptomatic hepatocellular carcinoma and its clinical implications.
Jin-Chuan Sheu,Juei-Low Sung,Ding-Shinn Chen,Pei-Ming Yang,Ming-Yang Lai,Chue-Shue Lee,Hey-Chi Hsu,Che-Nan Chuang,Pan-Chyr Yang,Teh-Hong Wang,Jaw-Town Lin,Cha-Ze Lee +11 more
TL;DR: In this article, the growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days.
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Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience
Ding-Shinn Chen,George Kuo,Juei-Low Sung,Ming-Yang Lai,Jin-Chuan Sheu,Pei-Jer Chen,Pei-Ming Yang,Hsu-Mei Hsu,Mei-Hwei Chang,Chien-Jen Chen,Liang-Cheng Hahn,Qui-Lim Choo,Teh-Hong Wang,Michael Houghton +13 more
TL;DR: HCV infection appears to play a relatively minor role in HBsAg-positive liver disease in Taiwan but is strongly associated with HBs Ag-negative chronic liver disease and HCC.
Journal ArticleDOI
Long-term efficacy of ribavirin plus interferon alfa in the treatment of chronic hepatitis C
Ming-Yang Lai,Jia-Horng Kao,Pei-Ming Yang,Jin-Town Wang,Pei-Jer Chen,Kin-Wei A. Chan,Jan-Show Chu,Ding-Shinn Chen +7 more
TL;DR: Combined treatment with ribavirin and interferon alfa 2a for 24 weeks is more effective than interfer on alfa2a alone for the treatment of chronic hepatitis C.