M
Ming Zhou
Researcher at Huazhong Agricultural University
Publications - 52
Citations - 831
Ming Zhou is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Rabies virus & Rabies. The author has an hindex of 12, co-authored 52 publications receiving 547 citations. Previous affiliations of Ming Zhou include University of Georgia.
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Journal ArticleDOI
Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs.
Clement W. Gnanadurai,Ming Zhou,Wenqi He,Christina M. Leyson,Chien-tsun Huang,Gregory W Salyards,Stephen B. Harvey,Zhenhai Chen,Biao He,Yang Yang,Yang Yang,Douglas C. Hooper,Berhnard Dietzchold,Zhen F. Fu,Zhen F. Fu +14 more
TL;DR: Non-lethal rabies infection in dogs experimentally infected with wild type dog rabies virus correlates with the presence of high level of virus neutralizing antibodies (VNA) in the cerebral spinal fluid (CSF) and mild immune cell accumulation in the central nervous system (CNS).
Journal ArticleDOI
Overexpression of Interleukin-7 Extends the Humoral Immune Response Induced by Rabies Vaccination.
Yingying Li,Ming Zhou,Zhaochen Luo,Yachun Zhang,Min Cui,Huanchun Chen,Zhen F. Fu,Zhen F. Fu,Ling Zhao +8 more
TL;DR: The results suggest that the expression of IL-7 is beneficial for induction of potent and long-lasting humoral immune responses following rabies vaccination, and overexpressing IL- 7 improved the induction of long- lasting primary and secondary antibody responses post-RABV immunization.
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Aptamer and RVG functionalized gold nanorods for targeted photothermal therapy of neurotropic virus infection in the mouse brain
TL;DR: Collectively, aptamer conjugated RVG-Apt-PEG-Silica AuNR-based PTT could be considered as a promising strategy for clinical treatment with neurotropic virus infection.
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Monophosphoryl-Lipid A (MPLA) is an Efficacious Adjuvant for Inactivated Rabies Vaccines.
Chen Chen,Chengguang Zhang,Ruiming Li,Zongmei Wang,Yueming Yuan,Haoqi Li,Zhen-fang Fu,Ming Zhou,Ling Zhao +8 more
TL;DR: Results demonstrate that MPLA serving as an adjuvant enhances the intensity of humoral immune responses by activating the cDC–Tfh–GC B axis, which will contribute to the improvement of the efficiency of traditional rabies vaccines.
Journal ArticleDOI
Enhancement of blood-brain barrier permeability is required for intravenously administered virus neutralizing antibodies to clear an established rabies virus infection from the brain and prevent the development of rabies in mice.
Chien-tsun Huang,Zhenguang Li,Ying Huang,Guoqing Zhang,Ming Zhou,Qingqing Chai,Hua Wu,Zhen F. Fu,Zhen F. Fu +8 more
TL;DR: It is demonstrated that exogenous administration of VNAs is crucial in the clearance of RABV from the brain and prevent the development of rabies in both immunocompetent and Immunocompromised mice as long as the BBB permeability remains enhanced.