M
Minkyung Kang
Researcher at New Generation University College
Publications - 9
Citations - 288
Minkyung Kang is an academic researcher from New Generation University College. The author has contributed to research in topics: Long-term potentiation & Excitatory postsynaptic potential. The author has an hindex of 6, co-authored 9 publications receiving 220 citations. Previous affiliations of Minkyung Kang include Chung-Ang University.
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Journal ArticleDOI
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome
Yong-Seok Lee,Dan Ehninger,Miou Zhou,Jun Young Oh,Minkyung Kang,Chuljung Kwak,Hyun Hee Ryu,Delana Hopkins Butz,Toshiyuki Araki,Ying Cai,J. Balaji,J. Balaji,Yoshitake Sano,Christine I. Nam,Hyong Kyu Kim,Bong-Kiun Kaang,Corinna Burger,Benjamin G. Neel,Alcino J. Silva +18 more
TL;DR: It is demonstrated that increased basal Erk activity and corresponding baseline increases in excitatory synaptic function are responsible for the LTP impairments and, consequently, the learning deficits in mouse models of NS.
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Impaired learning and memory in CD38 null mutant mice
Somi Kim,Tae Hyun Kim,Hye Ryeon Lee,Eun Hye Jang,Hyun Hee Ryu,Minkyung Kang,So Young Rah,Juyoun Yoo,Bolam Lee,Jae-Ick Kim,Chae Seok Lim,Sang Jeong Kim,Uh-Hyun Kim,Yong-Seok Lee,Bong-Kiun Kaang +14 more
TL;DR: The results provide convincing evidence that CD38−/− mice show deficits in various learning and memory tasks including spatial and non-spatial memory tasks and demonstrate thatCD38 is critical for regulating hippocampus-dependent learning andMemory without modulating synaptic plasticity.
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Fabrication of membranes for the liquid separation: Part 1. Ultrafiltration membranes prepared from novel miscible blends of polysulfone and poly(1-vinylpyrrolidone-co-acrylonitrile) copolymers
TL;DR: In this paper, poly(1-vinylpyrrolidone-co-acrylonitrile) copolymers were synthesized via radical copolymerization and then their blends with polysulfone (PSf) were used for the fabrication of ultrafiltration membranes having hydrophilic properties.
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The impact of RASopathy-associated mutations on CNS development in mice and humans
Minkyung Kang,Yong Seok Lee +1 more
TL;DR: Recent literatures that investigated the developmental role of RASopathy-associated mutations using mutant mice provided insights into the specific contribution of Ras-ERK signaling molecules to CNS development and the subsequent impact on cognitive function in adult mice.
Journal ArticleDOI
Excitatory neuron–specific SHP2-ERK signaling network regulates synaptic plasticity and memory
Hyun Hee Ryu,Hyun Hee Ryu,Tae Hyun Kim,Jung-Woong Kim,Minkyung Kang,Pojeong Park,Yong Gyu Kim,Hyopil Kim,Jiyeon Ha,Ja Eun Choi,Jisu Lee,Chae Seok Lim,Chul-Hong Kim,Sang Jeong Kim,Alcino J. Silva,Bong-Kiun Kaang,Yong Seok Lee +16 more
TL;DR: It is found that expressing the NS-associated mutant SHP2D61G in excitatory, but not inhibitory, hippocampal neurons increased ERK signaling and impaired both long-term potentiation (LTP) and spatial memory in mice, although endogenousSHP2 was expressed in both neuronal types.