U
Uh-Hyun Kim
Researcher at Chonbuk National University
Publications - 125
Citations - 4270
Uh-Hyun Kim is an academic researcher from Chonbuk National University. The author has contributed to research in topics: Cyclic ADP-ribose & Second messenger system. The author has an hindex of 35, co-authored 121 publications receiving 3758 citations. Previous affiliations of Uh-Hyun Kim include University of Minnesota & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+ increase are reciprocally modulated in rat cardiomyocytes.
Seon-Young Kim,Sang-Jin Kim,Byoung-Joo Kim,So-Young Rah,Sung Mo Chung,Mie-Jae Im,Uh-Hyun Kim +6 more
TL;DR: Doxorubicin-mediated ROS opens ryanodine receptor, resulting in an increase in Ca2+i and that the increased [Ca2+]i induces ROS production, suggesting that DOX/ROS-induced increase of [Ca 2+] i plays a critical role in damage of cardiomyocytes.
Journal ArticleDOI
Feedback regulation of phospholipase C-beta by protein kinase C.
TL;DR: It is proposed that rather than having a direct effect on enzyme activity, the phosphorylation of PLC-beta by PKC may alter its interaction with a putative guanine nucleotide-binding regulatory protein and thereby prevent its activation.
Journal ArticleDOI
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.
Toshio Munesue,Shigeru Yokoyama,Kazuhiko Nakamura,Ayyappan Anitha,Kazuo Yamada,Kenshi Hayashi,Tomoya Asaka,Hong-Xiang Liu,Duo Jin,Keita Koizumi,Mohammad Saharul Islam,Jian-Jun Huang,Wen Jie Ma,Uh-Hyun Kim,Sun Jun Kim,Keunwan Park,Dongsup Kim,Mitsuru Kikuchi,Yasuki Ono,Hideo Nakatani,Shiro Suda,Taishi Miyachi,Hirokazu Hirai,Alla B. Salmina,Yu A. Pichugina,Andrei A. Soumarokov,Nori Takei,Norio Mori,Masatsugu Tsujii,Toshiro Sugiyama,Kunimasa Yagi,Masakazu Yamagishi,Tsukasa Sasaki,Hidenori Yamasue,Nobumasa Kato,Ryota Hashimoto,Masako Taniike,Yutaka Hayashi,Jun-ichiro Hamada,Shioto Suzuki,Akishi Ooi,Mami Noda,Yuko Kamiyama,Mizuho A. Kido,Olga Lopatina,Minako Hashii,Sarwat Amina,Fabio Malavasi,Eric J. Huang,Jiasheng Zhang,Nobuaki Shimizu,Takeo Yoshikawa,Akihiro Matsushima,Yoshio Minabe,Haruhiro Higashida +54 more
TL;DR: The immunohistochemical expression of CD38 in the hypothalamus of post-mortem brains of non-ASD subjects is examined and it is found that CD38 was colocalized with OT in secretory neurons.
Journal ArticleDOI
Ca2+ Signaling Tools Acquired from Prostasomes Are Required for Progesterone-Induced Sperm Motility
Kwang-Hyun Park,Byung-Ju Kim,John Kang,Tae-Sik Nam,Jung Min Lim,Hyoung Tae Kim,Jong Kwan Park,Young Gon Kim,Soo-Wan Chae,Uh-Hyun Kim +9 more
TL;DR: It is shown that a long-lasting Ca2+ signal required for sperm motility in response to progesterone depends on their pH-dependent fusion with prostasomes, which are small vesicles secreted by the prostate.
Journal ArticleDOI
Tyrosine residues in bovine phospholipase C-gamma phosphorylated by the epidermal growth factor receptor in vitro.
TL;DR: It is proposed that the phosphorylation of PLC-gamma by EGF receptor kinase alters its interaction with putative inhibitory proteins and leads to its activation.