M
Minoru Matsui
Researcher at University of Tokyo
Publications - 31
Citations - 2270
Minoru Matsui is an academic researcher from University of Tokyo. The author has contributed to research in topics: Muscarinic acetylcholine receptor & Muscarinic acetylcholine receptor M3. The author has an hindex of 22, co-authored 31 publications receiving 2146 citations. Previous affiliations of Minoru Matsui include Chiba Institute of Science & Kyoto University.
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Journal ArticleDOI
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling.
Yuko Fukudome,Takako Ohno-Shosaku,Minoru Matsui,Yuko Omori,Masahiro Fukaya,Hiroshi Tsubokawa,Makoto Mark Taketo,Masahiko Watanabe,Toshiya Manabe,Masanobu Kano +9 more
TL;DR: The muscarinic system can influence hippocampal functions by controlling different subsets of inhibitory synapses through the two distinct mechanisms, namely a cannabinoid‐dependent and cannabinoid‐independent mechanism.
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Modulation of Synaptic Plasticity by Physiological Activation of M1 Muscarinic Acetylcholine Receptors in the Mouse Hippocampus
TL;DR: It is found that a low concentration of carbachol enhanced long-term potentiation (LTP) of excitatory synaptic transmission in mouse hippocampal slices and suggested that physiologically released ACh from cholinergic fibers modulates hippocampal synaptic plasticity through the postsynaptic M1 mAChR activation.
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Mice Lacking M2 and M3 Muscarinic Acetylcholine Receptors Are Devoid of Cholinergic Smooth Muscle Contractions But Still Viable
Minoru Matsui,Daisuke Motomura,Toru Fujikawa,Jian Jiang,Shin ichi Takahashi,Toshiya Manabe,Makoto Mark Taketo,Makoto Mark Taketo +7 more
TL;DR: It is suggested that an additional mechanism operates in the control of pupillary constriction–dilatation, contrary to the well known cholinergic constriction, which is dispensable in gastrointestinal motility and female urination.
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Preferential Localization of Muscarinic M1 Receptor on Dendritic Shaft and Spine of Cortical Pyramidal Cells and Its Anatomical Evidence for Volume Transmission
TL;DR: The results suggest that M1 is so positioned to sense ambient ACh released from cholinergic varicosities at variable distances, and to enhance the synaptic efficacy and excitability of pyramidal cells, that molecular–anatomical arrangements will provide the evidence for volume transmission, at least in M1-mediated corticalCholinergic signaling.
Journal ArticleDOI
Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus.
Takako Ohno-Shosaku,Minoru Matsui,Yuko Fukudome,Jumpei Shosaku,Hiroshi Tsubokawa,Makoto Mark Taketo,Makoto Mark Taketo,Toshiya Manabe,Toshiya Manabe,Masanobu Kano +9 more
TL;DR: Results indicate that the activation of postsynaptic M1 and M3 receptors facilitates the depolarization‐induced release of endocannabinoids.