M
Minru Liao
Researcher at Sichuan University
Publications - 8
Citations - 186
Minru Liao is an academic researcher from Sichuan University. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 2, co-authored 4 publications receiving 10 citations.
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Journal ArticleDOI
Regulated cell death (RCD) in cancer: key pathways and targeted therapies
Fu Peng,Minru Liao,Rui Qin,Shiou Zhu,Cheng Peng,Leilei Fu,Yi Chen,Bok Ryul Yoo and Joon Soo Han +7 more
TL;DR: In this article , the authors focus on summarizing not only the key apoptotic and autophagy-dependent cell death signaling pathways, but also the crucial pathways of other RCD subroutines, including necroptosis, pyroptosis and lysosome dependent cell death.
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Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions.
TL;DR: In this paper, the authors summarized the current situation of a series of candidate small-molecule drugs in triple negative breast cancer (TNBC) therapy, including single-target drugs, dual target drugs, as well as drug repurposing and combination strategies.
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Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy
Chengcan Yang,Jifa Zhang,Minru Liao,Yushang Yang,Yuxi Wang,Yong Yuan,Liang Ouyang,Liang Ouyang +7 more
TL;DR: Current understanding of the functions of folate-metabolizing enzymes, especially SHMT2 and MTHFD2, are outlined, discussing their expression, potential functions, and regulatory mechanism in cancers.
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Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies
TL;DR: In this paper , the authors focus on summarizing the molecular mechanisms of the above-mentioned seven major RCD subroutines related to triple negative breast cancer (TNBC) and the latest progress of small-molecule compounds targeting different RCD subsroutine.
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Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models
TL;DR: In this paper , the main active components of Si-Miao-Yong-An decoction (SMYAD) were identified based on UL-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLCQ/TOF-MS) results.