M
Mira Rosenblat
Researcher at Technion – Israel Institute of Technology
Publications - 100
Citations - 11540
Mira Rosenblat is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Cholesterol & Oxidative stress. The author has an hindex of 44, co-authored 100 publications receiving 10970 citations. Previous affiliations of Mira Rosenblat include Rambam Health Care Campus & Rappaport Faculty of Medicine.
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Journal ArticleDOI
Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.
Michael Aviram,Mira Rosenblat,Charles L. Bisgaier,Roger S. Newton,S. L. Primo-Parmo,B N La Du +5 more
TL;DR: It is concluded that HDL-associated PON possesses peroxidase-like activity that can contribute to the protective effect of PON against lipoprotein oxidation, and may be a major contributor to the antiatherogenicity of this lipop Protein.
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Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice
Michael Aviram,Leslie Dornfeld,Mira Rosenblat,Nina Volkova,Marielle Kaplan,Raymond Coleman,Tony Hayek,Dita Presser,Bianca Fuhrman +8 more
TL;DR: Pomegranate juice had potent antiatherogenic effects in healthy humans and in atherosclerotic mice that may be attributable to its antioxidative properties.
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Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants.
Michael Aviram,Mira Rosenblat,Scott S. Billecke,John Erogul,Robert C. Sorenson,Charles L. Bisgaier,Roger S. Newton,Bert N. La Du +7 more
TL;DR: PON's ability to protect LDL against oxidation is accompanied by inactivation of the enzyme, suggesting the interaction of oxidized lipids in Ox-LDL with the PON's free sulfhydryl group.
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Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation
Michael Aviram,Mira Rosenblat,Diana Gaitini,Samy Nitecki,Aaron Hoffman,Leslie Dornfeld,Nina Volkova,Dita Presser,Judith Attias,Harley Liker,Tony Hayek +10 more
TL;DR: It is suggested that pomegranate juice consumption by patients with CAS decreases carotid IMT and systolic blood pressure and these effects could be related to the potent antioxidant characteristics of PJ polyphenols.
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Reduced Progression of Atherosclerosis in Apolipoprotein E–Deficient Mice Following Consumption of Red Wine, or Its Polyphenols Quercetin or Catechin, Is Associated With Reduced Susceptibility of LDL to Oxidation and Aggregation
Tony Hayek,Bianca Fuhrman,Jacob Vaya,Mira Rosenblat,Paula Belinky,Raymond Coleman,Avishay Elis,Michael Aviram +7 more
TL;DR: Dietary consumption by E degree mice of red wine or its polyphenolic flavonoids quercetin and, to a lesser extent, catechin leads to attenuation in the development of the atherosclerotic lesion, and this effect is associated with reduced susceptibility of their LDL to oxidation and aggregation.