M
Misun Won
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 87
Citations - 2548
Misun Won is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Cancer cell & RHOB. The author has an hindex of 22, co-authored 82 publications receiving 2165 citations. Previous affiliations of Misun Won include University of Science and Technology & Dongguk University.
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Journal ArticleDOI
Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe
Dong-Uk Kim,Jacqueline Hayles,Dongsup Kim,Valerie Wood,Valerie Wood,Han Oh Park,Misun Won,Hyang Sook Yoo,Trevor Duhig,Miyoung Nam,Georgia Palmer,Sangjo Han,Linda Jeffery,Seung Tae Baek,Hye-Mi Lee,Young Sam Shim,Minho Lee,Lila Kim,Kyung-Sun Heo,Eun Joo Noh,Ah Reum Lee,Young Joo Jang,Kyung Sook Chung,Shin Jung Choi,Jo Young Park,Young Woo Park,Hwan Mook Kim,Song Kyu Park,Hae Joon Park,Eun Jung Kang,Hyong Bai Kim,Hyun Sam Kang,Hee-Moon Park,Kyunghoon Kim,Kiwon Song,Kyung Bin Song,Paul Nurse,Paul Nurse,Kwang Lae Hoe +38 more
TL;DR: It is shown that fission yeast has more essential genes than budding yeast and that essential genes are more likely than nonessential genes to be present in a single copy, to be broadly conserved and to contain introns.
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Antioxidant activities of distiller dried grains with solubles as protein films containing tea extracts and their application in the packaging of pork meat
TL;DR: It is indicated that the DP films containing green tea extracts can be utilized as an anti-oxidative packaging material for pork meat.
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LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line
Kyeong Lee,Jung Eun Kang,Song-Kyu Park,Yinglan Jin,Kyung-Sook Chung,Hwan-Mook Kim,Kiho Lee,Moo Rim Kang,Myung Kyu Lee,Kyung Bin Song,Eun Gyeong Yang,Jung-Jun Lee,Misun Won +12 more
TL;DR: In mice carrying xenografts of human colon cancer HCT116 cells, LW6 demonstrated strong anti-tumor efficacy in vivo and caused a decrease in HIF-1alpha expression in frozen-tissue immunohistochemical staining, suggesting that LW6 may be valuable in the development of a Hif-1 alpha inhibitor for cancer treatment.
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Inactivation kinetics of Listeria monocytogenes, Salmonella enterica serovar Typhimurium, and Campylobacter jejuni in ready-to-eat sliced ham using UV-C irradiation
TL;DR: UV-C irradiation can be used as a microbial inactivation method for ready-to-eat sliced ham, and inactivation kinetics of the foodborne pathogens fit the Weibull model better than the first-order kinetics model.
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Identification of Malate Dehydrogenase 2 as a Target Protein of the HIF‐1 Inhibitor LW6 using Chemical Probes
Kyeong Lee,Hyun Seung Ban,Ravi Naik,Ye Seul Hong,Seohyun Son,Bokyung Kim,Yan Xia,Kyung Bin Song,Hong-Sub Lee,Misun Won +9 more
TL;DR: To identify a drug target, chemical biological methods such as activity-based probes (ABPs), photoaffinity labeling, biotinylation, and click conjugation have been used and it is found that compound 2 was localized primarily in the cytoplasm (Figure 1C) and the cellular localization of probe 2 was determined by a click reaction with an azidelinked Alexa Fluor 488 molecule.