M
Mitchell Singer
Researcher at University of California, Davis
Publications - 39
Citations - 2727
Mitchell Singer is an academic researcher from University of California, Davis. The author has contributed to research in topics: Myxococcus xanthus & Mutant. The author has an hindex of 19, co-authored 39 publications receiving 2619 citations. Previous affiliations of Mitchell Singer include Stanford University & University of Wisconsin-Madison.
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Journal ArticleDOI
A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea.
Dongying Wu,Dongying Wu,Philip Hugenholtz,Konstantinos Mavromatis,Rüdiger Pukall,Eileen Dalin,Natalia Ivanova,Victor Kunin,Lynne Goodwin,Martin Wu,Brian J. Tindall,Sean D. Hooper,Amrita Pati,Athanasios Lykidis,Stefan Spring,Iain Anderson,Patrik D'haeseleer,Patrik D'haeseleer,Adam Zemla,Mitchell Singer,Alla Lapidus,Matt Nolan,Alex Copeland,Cliff Han,Feng Chen,Jan Fang Cheng,Susan Lucas,Cheryl A. Kerfeld,Elke Lang,Sabine Gronow,Patrick S. G. Chain,Patrick S. G. Chain,David Bruce,Edward M. Rubin,Nikos C. Kyrpides,Hans-Peter Klenk,Jonathan A. Eisen,Jonathan A. Eisen +37 more
TL;DR: The results strongly support the need for systematic ‘phylogenomic’ efforts to compile a phylogeny-driven ‘Genomic Encyclopedia of Bacteria and Archaea’ in order to derive maximum knowledge from existing microbial genome data as well as from genome sequences to come.
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A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.
Mitchell Singer,Tania A. Baker,G Schnitzler,S M Deischel,M Goel,W Dove,K J Jaacks,Alan D. Grossman,James W. Erickson,Carol A. Gross +9 more
TL;DR: A collection of 182 isogenic strains containing genetically linked antibiotic resistance elements located at approximately 1-min intervals around the Escherichia coli chromosome, designed to be used in a rapid two-step mapping system in E. coli.
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The guanosine nucleotide (p)ppGpp initiates development and A-factor production in Myxococcus xanthus
TL;DR: A model in which accumulation of (p)ppGpp, in response to starvation, initiates the program of fruiting body development, including the production of A-factor, is supported.
Journal ArticleDOI
Ectopic production of guanosine penta- and tetraphosphate can initiate early developmental gene expression in Myxococcus xanthus.
Mitchell Singer,Dale Kaiser +1 more
TL;DR: The results suggest that M. xanthus cells can assess their nutritional status by monitoring the internal availability of amino acids through (p)ppGpp levels.
Journal ArticleDOI
Identification of Additional Players in the Alternative Biosynthesis Pathway to Isovaleryl‐CoA in the Myxobacterium Myxococcus xanthus
Helge B. Bode,Michael W. Ring,Gertrud Schwär,Matthias Altmeyer,Carsten Kegler,Ivy R. Jose,Mitchell Singer,Rolf Müller +7 more
TL;DR: It is shown that the proteins required for leucine degradation are also involved in the alternative IV‐CoA biosynthesis pathway through the efficient catalysis of the reverse reactions.