A
Alex Copeland
Researcher at Joint Genome Institute
Publications - 182
Citations - 16284
Alex Copeland is an academic researcher from Joint Genome Institute. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 41, co-authored 180 publications receiving 13973 citations. Previous affiliations of Alex Copeland include Lawrence Berkeley National Laboratory & United States Department of Energy.
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Journal ArticleDOI
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data
Chen-Shan Chin,David Alexander,Patrick Marks,Aaron Klammer,James P Drake,Cheryl Heiner,Alicia Clum,Alex Copeland,John Huddleston,Evan E. Eichler,Stephen Turner,Jonas Korlach +11 more
TL;DR: This work presents a hierarchical genome-assembly process (HGAP) for high-quality de novo microbial genome assemblies using only a single, long-insert shotgun DNA library in conjunction with Single Molecule, Real-Time (SMRT) DNA sequencing.
Journal ArticleDOI
The paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes
Dimitrios Floudas,Manfred Binder,Robert Riley,Kerrie Barry,Robert A. Blanchette,Bernard Henrissat,Ángel T. Martínez,Robert Otillar,Joseph W. Spatafora,Jagjit S. Yadav,Andrea Aerts,Isabelle Benoit,Alexander Boyd,Alexis Carlson,Alex Copeland,Pedro M. Coutinho,Ronald P. de Vries,Patricia Ferreira,Keisha Findley,Brian Foster,Jill Gaskell,Dylan Glotzer,Paweł Górecki,Joseph Heitman,Cedar N. Hesse,Chiaki Hori,Kiyohiko Igarashi,Joel A. Jurgens,Nathan M Kallen,Phil Kersten,Annegret Kohler,Ursula Kües,T. K. Arun Kumar,Alan Kuo,Kurt LaButti,Luis F. Larrondo,Erika Lindquist,Albee Y. Ling,Vincent Lombard,Susan Lucas,Taina Lundell,Rachael Martin,David J. McLaughlin,Ingo Morgenstern,Emanuelle Morin,Claude Murat,László Nagy,Matthew J Nolan,Robin A. Ohm,Aleksandrina Patyshakuliyeva,Antonis Rokas,Francisco J. Ruiz-Dueñas,Grzegorz Sabat,Asaf Salamov,Masahiro Samejima,Jeremy Schmutz,Jason C. Slot,Franz J. St John,Jan Stenlid,Hui Sun,Sheng Sun,Khajamohiddin Syed,Adrian Tsang,Ad Wiebenga,Darcy Young,Antonio G. Pisabarro,Daniel C. Eastwood,Francis Martin,Dan Cullen,Igor V. Grigoriev,David S. Hibbett +70 more
TL;DR: Comparative analyses of 31 fungal genomes suggest that lignin-degrading peroxidases expanded in the lineage leading to the ancestor of the Agaricomycetes, which is reconstructed as a white rot species, and then contracted in parallel lineages leading to brown rot and mycorrhizal species.
Journal ArticleDOI
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
Robert M. Bowers,Nikos C. Kyrpides,Ramunas Stepanauskas,Miranda Harmon-Smith,Devin F. R. Doud,T. B. K. Reddy,Frederik Schulz,Jessica K. Jarett,Adam R. Rivers,Adam R. Rivers,Emiley A. Eloe-Fadrosh,Susannah G. Tringe,Susannah G. Tringe,Natalia Ivanova,Alex Copeland,Alicia Clum,Eric D. Becraft,Rex R. Malmstrom,Bruce W. Birren,Mircea Podar,Peer Bork,George M. Weinstock,George M. Garrity,Jeremy A. Dodsworth,Shibu Yooseph,Granger G. Sutton,Frank Oliver Gloeckner,Jack A. Gilbert,William C. Nelson,Steven J. Hallam,Sean P. Jungbluth,Sean P. Jungbluth,Thijs J. G. Ettema,Scott Tighe,Konstantinos T. Konstantinidis,Wen Tso Liu,Brett J. Baker,Thomas Rattei,Jonathan A. Eisen,Brian P. Hedlund,Katherine D. McMahon,Noah Fierer,Rob Knight,Robert D. Finn,Guy Cochrane,Ilene Karsch-Mizrachi,Gene W. Tyson,Christian Rinke,Alla Lapidus,Folker Meyer,Pelin Yilmaz,Donovan H. Parks,A. M. Eren,Lynn M. Schriml,Jillian F. Banfield,Philip Hugenholtz,Tanja Woyke +56 more
TL;DR: Two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences are presented, including the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum information about a Metagenome-Assembled Genomes (MIMAG), including estimates of genome completeness and contamination.
Journal ArticleDOI
A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea.
Dongying Wu,Dongying Wu,Philip Hugenholtz,Konstantinos Mavromatis,Rüdiger Pukall,Eileen Dalin,Natalia Ivanova,Victor Kunin,Lynne Goodwin,Martin Wu,Brian J. Tindall,Sean D. Hooper,Amrita Pati,Athanasios Lykidis,Stefan Spring,Iain Anderson,Patrik D'haeseleer,Patrik D'haeseleer,Adam Zemla,Mitchell Singer,Alla Lapidus,Matt Nolan,Alex Copeland,Cliff Han,Feng Chen,Jan Fang Cheng,Susan Lucas,Cheryl A. Kerfeld,Elke Lang,Sabine Gronow,Patrick S. G. Chain,Patrick S. G. Chain,David Bruce,Edward M. Rubin,Nikos C. Kyrpides,Hans-Peter Klenk,Jonathan A. Eisen,Jonathan A. Eisen +37 more
TL;DR: The results strongly support the need for systematic ‘phylogenomic’ efforts to compile a phylogeny-driven ‘Genomic Encyclopedia of Bacteria and Archaea’ in order to derive maximum knowledge from existing microbial genome data as well as from genome sequences to come.
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Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists.
Annegret Kohler,Annegret Kohler,Alan Kuo,László Nagy,László Nagy,Emmanuelle Morin,Emmanuelle Morin,Kerrie Barry,François Buscot,Björn Canbäck,Cindy Choi,Nicolas Cichocki,Nicolas Cichocki,Alicia Clum,Jan V. Colpaert,Alex Copeland,Maurício Dutra Costa,Jeanne Doré,Dimitrios Floudas,Mariangela Girlanda,Bernard Henrissat,Bernard Henrissat,Sylvie Herrmann,Jaqueline Hess,Nils Högberg,Tomas Johansson,Hassine-Radhouane Khouja,Kurt LaButti,Urs Lahrmann,Anthony Levasseur,Erika Lindquist,Anna Lipzen,Roland Marmeisse,Elena Martino,Elena Martino,Claude Murat,Claude Murat,Chew Yee Ngan,Uwe Nehls,Jonathan M. Plett,Jonathan M. Plett,Anne Pringle,Robin A. Ohm,Silvia Perotto,Martina Peter,Robert Riley,Francois Rineau,Francois Rineau,Joske Ruytinx,Asaf Salamov,Firoz Shah,Hui Sun,Mika T. Tarkka,Andrew Tritt,Claire Veneault-Fourrey,Claire Veneault-Fourrey,Alga Zuccaro,Alga Zuccaro,Anders Tunlid,Igor V. Grigoriev,David S. Hibbett,Francis Martin,Francis Martin +62 more
TL;DR: Convergent evolution of the mycorrhizal habit in fungi occurred via the repeated evolution of a 'symbiosis toolkit', with reduced numbers of PCWDEs and lineage-specific suites of myCorrhiza-induced genes.