Mohamed Tarek Badr

TL;DR: The identification of a common gene signature and pathways substantiates the observation of an epidemiological association of TB and RA and provides clues on the mechanistic basis of this association.

TL;DR: In this article , the authors tested whether spontaneously appearing micronuclei in cancer cells are linked to sub-lethal apoptotic signals and found that low-level activity in the mitochondrial apoptosis apparatus operates through CAD-dependent gene induction and STING-activation and has substantial impact on metastasis in cancer patients.

TL;DR: In this article , the authors show that the host cell's mitochondrial apoptosis system contributes to cytokine secretion and DNA-damage in the absence of cell death, and that DNA damage through sub-lethal mitochondrial signals is likely to contribute to mutagenesis and cancer development.

TL;DR: Metronidazole and other β-lactam/β- lactamase inhibitor combinations such as ampicillin-sulbactam remain suitable for empirical treatment of infections with anaerobic bacteria.

TL;DR: In this article, the authors used next-and third-generation sequencing (NGS) methods to identify responsible pathogenic bacteria in ascitic fluid infections, in order to improve patients care and to guide empirical therapy.