M
Mohammad Bonakdar
Researcher at Virginia Tech
Publications - 19
Citations - 370
Mohammad Bonakdar is an academic researcher from Virginia Tech. The author has contributed to research in topics: Finite element method & Modal analysis. The author has an hindex of 10, co-authored 19 publications receiving 302 citations. Previous affiliations of Mohammad Bonakdar include Sharif University of Technology.
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Journal ArticleDOI
Improving cancer therapies by targeting the physical and chemical hallmarks of the tumor microenvironment
TL;DR: The physical and chemical hallmarks of the TME are summarized, and how these tumor characteristics either currently are, or may ultimately be targeted to improve cancer therapies are discussed.
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A microfluidic model of the blood–brain barrier to study permeabilization by pulsed electric fields
TL;DR: A microfluidic platform for real-time measurement of BBB permeability pre- and post-treatment with pulsed electric fields is developed and found that this device is able to capture real- time permeability of hCMEC monolayers for both reversible and irreversible electroporation pulsing regimes.
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Effects of internal electrode cooling on irreversible electroporation using a perfused organ model.
Timothy J. O’Brien,Mohammad Bonakdar,Suyashree Bhonsle,Robert E. Neal,Charles Aardema,John L. Robertson,S. Nahum Goldberg,Rafael V. Davalos +7 more
TL;DR: The internally-cooled bipolar applicator offers advantages that could improve clinical outcomes and Thermally mitigating internal perfusion technology reduced tissue temperatures and electric current while maintaining similar lesion sizes.
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The Feasibility of a Smart Surgical Probe for Verification of IRE Treatments Using Electrical Impedance Spectroscopy
TL;DR: It is shown that electrical impedance spectroscopy could be used as a technique for treatment verification, and when combined with appropriate FEM modeling can determine the lesion dimensions.
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Characterization of Irreversible Electroporation Ablation with a Validated Perfused Organ Model.
Suyashree Bhonsle,Mohammad Bonakdar,Robert E. Neal,Charles Aardema,John L. Robertson,Jonathon Howarth,Helen Kavnoudias,Kenneth R. Thomson,S. Nahum Goldberg,Rafael V. Davalos +9 more
TL;DR: The perfused organ model provides an alternative to animal trials for investigation of IRE treatments and may have an important role in the future development of new devices, algorithms, and techniques for this therapy.