M
Mohammed W. Al-Rabia
Researcher at King Abdulaziz University
Publications - 53
Citations - 337
Mohammed W. Al-Rabia is an academic researcher from King Abdulaziz University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 7, co-authored 36 publications receiving 148 citations. Previous affiliations of Mohammed W. Al-Rabia include King Saud bin Abdulaziz University for Health Sciences.
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Journal ArticleDOI
Intranasal Niosomal In Situ Gel as a Promising Approach for Enhancing Flibanserin Bioavailability and Brain Delivery: In Vitro Optimization and Ex Vivo/In Vivo Evaluation.
Usama A. Fahmy,Shaimaa M Badr-Eldin,Shaimaa M Badr-Eldin,Osama A. A. Ahmed,Hibah M. Aldawsari,Singkome Tima,Hani Z. Asfour,Mohammed W. Al-Rabia,Aya A. Negm,Muhammad Hadi Sultan,Osama Madkhali,Nabil A. Alhakamy +11 more
TL;DR: The optimized FLB niosomes integrated into gellan gum-based in situ gel exhibited enhanced ex vivo permeation and improved plasma and brain concentrations after nasal administration in rats compared to raw FLB.
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Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells.
Nabil A. Alhakamy,Shaimaa M Badr-Eldin,Shaimaa M Badr-Eldin,Osama A. A. Ahmed,Hani Z. Asfour,Hibah M. Aldawsari,Mardi M. Algandaby,Basma G. Eid,Ashraf B. Abdel-Naim,Zuhier Awan,Adel F. Alghaith,Ahmed L. Alaofi,Amir I Mohamed,Solomon Z Okbazghi,Mohammed W. Al-Rabia,Usama A. Fahmy +15 more
TL;DR: PIC-E exhibited superior cell death-inducing activities against HCT 116 cells as compared to pure PIC, mediated, at least partly, by enhanced pro-apoptotic activity, disruption of MMP, and stimulation of ROS generation.
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Repurposing of Sitagliptin- Melittin Optimized Nanoformula against SARS-CoV-2: Antiviral Screening and Molecular Docking Studies
Mohammed W. Al-Rabia,Nabil A. Alhakamy,Osama A. A. Ahmed,Khalid Eljaaly,Khalid Eljaaly,Ahmed L. Aloafi,Ahmed Mostafa,Hani Z. Asfour,Ahmed Aldarmahi,Khaled M. Darwish,Tarek S. Ibrahim,Usama A. Fahmy +11 more
TL;DR: In this article, the authors evaluated the efficacy of the combined complex of Sitagliptin (SIT) with melittin (MEL) against SARS-CoV-2 virus.
Journal ArticleDOI
Anti-inflammatory ergosterol derivatives from the endophytic fungus Fusarium chlamydosporum.
Mohammed W. Al-Rabia,Gamal A. Mohamed,Gamal A. Mohamed,Sabrin R.M. Ibrahim,Sabrin R.M. Ibrahim,Hani Z. Asfour +5 more
TL;DR: Two new ergosterol derivatives separated from the EtOAc extract of the endophytic fungus Fusarium chlamydosporum isolated from Anvillea garcinii (Asteraceae) leaves growing in Saudi Arabia showed moderate 5-LOX inhibitory potential compared to indomethacin.
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The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells.
Zuhier Awan,Usama A. Fahmy,Shaimaa M Badr-Eldin,Shaimaa M Badr-Eldin,Tarek S. Ibrahim,Hani Z. Asfour,Mohammed W. Al-Rabia,Anas Alfarsi,Nabil A. Alhakamy,Wesam H. Abdulaal,Hadeel Al Sadoun,Nawal Helmi,Ahmad O. Noor,Filippo Caraci,Diena M. Almasri,Giuseppe Caruso +15 more
TL;DR: SMV-EMLs demonstrated superior cell death-inducing activity against MCF-7 cells compared to pure SMV, mediated, at least in part, by enhanced pro-apoptotic activity and MMP modulation of SMV.