M
Monique Chambon
Researcher at University of Montpellier
Publications - 9
Citations - 427
Monique Chambon is an academic researcher from University of Montpellier. The author has contributed to research in topics: Cell culture & Cancer cell. The author has an hindex of 8, co-authored 9 publications receiving 407 citations. Previous affiliations of Monique Chambon include French Institute of Health and Medical Research & University of Clermont-Ferrand.
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Journal ArticleDOI
Estrogen-induced lysosomal proteases secreted by breast cancer cells: a role in carcinogenesis?
Henri Rochefort,Françoise Capony,Marcel Garcia,Vincent Cavaillès,Gilles Freiss,Monique Chambon,Muriel Morisset,Françoise Vignon +7 more
TL;DR: The 52K cathepsin‐D‐like protease is the first example of a lysosomal protease induced by estrogens in cancer cells, and results obtained using different approaches suggest that two cysteinyl cat hepsins are also related to cell transformation and invasiveness.
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Prognostic Significance of TRIM24/TIF-1α Gene Expression in Breast Cancer
Monique Chambon,Monique Chambon,Béatrice Orsetti,Béatrice Orsetti,Marie-Laurence Berthe,Caroline Bascoul-Mollevi,Carmen Rodríguez,Carmen Rodríguez,Vanessa Duong,Vanessa Duong,Michel Gleizes,Michel Gleizes,Sandrine Thénot,Sandrine Thénot,Frédéric Bibeau,Charles Theillet,Charles Theillet,Vincent Cavaillès,Vincent Cavaillès +18 more
TL;DR: This work is the first study that shows that overexpression of the TRIM24/TIF-1α gene in breast cancer is associated with poor prognosis and worse survival, and it suggests that this transcription coregulator may play a role in mammary carcinogenesis and represent a novel prognostic marker.
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Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells.
Philippe Nirdé,Danielle Derocq,Marie Maynadier,Monique Chambon,Ilaria Basile,Magali Gary-Bobo,Marcel Garcia +6 more
TL;DR: A new role of this secreted hsc70 chaperone in cell proliferation that might account for the higher tumor growth of cancer cells overexpressing cath D is suggested.
Journal ArticleDOI
BRCA1 protein and nucleolin colocalize in breast carcinoma tissue and cancer cell lines.
Natalie Tulchin,Monique Chambon,Gloria Juan,Steven Dikman,James A. Strauchen,Leonard Ornstein,Blase Billack,Nicholas T. Woods,Alvaro N.A. Monteiro +8 more
TL;DR: The observed colocalization of BRCA1 and nucleolin raises new possibilities for the nucleoplasm-nucleolus pathways of these proteins and their functional significance.
Journal Article
Effect of Estradiol on Nonmalignant Human Mammary Cells in Primary Culture
Monique Chambon,Ghislaine Cavalie-Barthez,Frédéric Veith,Françoise Vignon,Richard Hallowes,Henri Rochefort +5 more
TL;DR: In this article, the effects of estradiol on primary cultures of nonmalignant human mammary tissue collected surgically from fibroadenomas or during reduction mammoplasties were studied.