Morag Chisholm

TL;DR: Three individuals of Greek or Greek Cypriot origin with an atypical form of HbH disease characterized by a severe hypochromic microcytic anaemia associated with relatively small amounts of HBH in the peripheral blood are identified.

TL;DR: A case history and functional data are presented on another 48‐year‐old severe haemophilia B patient (UK232) with a different (G → A) mutation at the same position, −26, which strengthens the evidence for the importance of nucleotide −26 for the normal transcription of the gene in response to HNF4 and for the proposed Leyden recovery mechanism in responded to AR and testosterone acting directly through the factor IX ARE.

TL;DR: An infant with a giant cavernous haemangioma developed a severe consumption coagulopathy and systemic bleeding, and replacement therapy with cryoprecipitate produced only a transient improvement in the abnormal clotting, but the addition of tranexamic acid resulted in sustained correction, permitting corrective surgery to be performed.

TL;DR: A case of acquired von Willebrand's disease with severe and persistent gastro‐intestinal bleeding from multiple bleeding points is reported and the patient received maximum substitution treatment including factor VIII concentrates, cryoprecipitate and platelets.

TL;DR: The suggestion that heterozygous protein C deficiency contributes to the risk of arterial stroke was not supported by this study.