M
Muhammad Ashraf
Researcher at Islamia University
Publications - 173
Citations - 2550
Muhammad Ashraf is an academic researcher from Islamia University. The author has contributed to research in topics: Docking (molecular) & Chemistry. The author has an hindex of 23, co-authored 149 publications receiving 1678 citations. Previous affiliations of Muhammad Ashraf include University of the Punjab & Bahauddin Zakariya University.
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Triazinoindole analogs as potent inhibitors of α-glucosidase: synthesis, biological evaluation and molecular docking studies.
Fazal Rahim,Khadim Ullah,Hayat Ullah,Abdul Wadood,Muhammad Taha,Ashfaq Ur Rehman,Imad Uddin,Muhammad Ashraf,Ayesha Shaukat,Wajid Rehman,Shafqat Hussain,Khalid Mohammed Khan +11 more
TL;DR: A new series of triazinoindole analogs 1-11 were synthesized, characterized by EI-MS and (1)H NMR, evaluated for α-glucosidase inhibitory potential, and showed good enzyme inhibition.
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Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease.
Fazal Rahim,Muhammad Tariq Javed,Hayat Ullah,Abdul Wadood,Muhammad Taha,Muhammad Ashraf,Qurat-ul-Ain,Muhammad Anas Khan,Fahad Khan,Salma Mirza,Khalid Mohammed Khan +10 more
TL;DR: A series of thirty thiazole analogs were prepared, characterized by (1)H NMR, (13)C NMR and EI-MS and evaluated for Acetylcholinesterase and butyrylcholiersterase inhibitory potential, and exhibited well to moderate enzyme inhibition.
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Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase.
Fazal Rahim,Hayat Ullah,Muhammad Javid,Abdul Wadood,Muhammad Taha,Muhammad Ashraf,Ayesha Shaukat,Muhammad Junaid,Shafqat Hussain,Wajid Rehman,Rashad Mehmood,Muhammad Sajid,Muhammad Naseem Khan,Khalid Mohammed Khan +13 more
TL;DR: A series of thiazole derivatives 1-21 were prepared, characterized by EI-MS and (1)H NMR and evaluated for α-glucosidase inhibitory potential and studies showed these thiazoles analogs as a new class of α- glucoside inhibitors.
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Synthesis of 4-thiazolidinone analogs as potent in vitro anti-urease agents.
Fazal Rahim,Khalid Zaman,Hayat Ullah,Muhammad Taha,Abdul Wadood,Muhammad Tariq Javed,Wajid Rehman,Muhammad Ashraf,Reaz Uddin,Imad Uddin,Humna Asghar,Aftab Ahmad Khan,Khalid Mohammed Khan +12 more
TL;DR: Eight derivatives of 4-Thiazolidinone analogs 1-20 showed outstanding urease inhibitory potential, which is better than the standard thiourea, and the remaining analogs showed good to excellent u rerease inhibition.
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Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases.
Fazal Rahim,Hayat Ullah,Muhammad Taha,Abdul Wadood,Muhammad Tariq Javed,Wajid Rehman,Mohsan Nawaz,Muhammad Ashraf,Muhammad Ali,Muhammad Sajid,Farman Ali,Muhammad Naseem Khan,Khalid Mohammed Khan +12 more
TL;DR: Twenty-eight analogs of hydrazide based Schiff bases are synthesized, characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase and butyrylcholiersterase inhibition, and structure activity relationship has been established.