M
Murray P. Deutscher
Researcher at University of Miami
Publications - 184
Citations - 11738
Murray P. Deutscher is an academic researcher from University of Miami. The author has contributed to research in topics: RNase P & RNase PH. The author has an hindex of 60, co-authored 184 publications receiving 11193 citations. Previous affiliations of Murray P. Deutscher include University of Connecticut Health Center & National Institute for Medical Research.
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Journal ArticleDOI
Purification and structural characterization of rat liver threonyl transfer ribonucleic acid synthetase
TL;DR: Threonyl-tRNA synthetase was purified approximately 500-fold from a high-speed supernatant fraction of rat liver and appears to be an alpha 2 dimer, while preliminary carbohydrate analyses suggested that the enzyme is a glycoprotein.
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The gene for the longest known Escherichia coli protein is a member of helicase superfamily II
TL;DR: The Escherichia coli rnt gene, which encodes the RNA-processing enzyme RNase T, is cotranscribed with a downstream gene, making it the longest known protein in E. coli and suggesting that very large helicases are present in this organism.
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Escherichia coli RNase D. Catalytic properties and substrate specificity.
TL;DR: Study of the mode of action of RNase D indicates that it is an exonuclease which initiates hydrolysis at the 3'-terminus and removes 5'-mononucleotides in a random fashion, and the relation of these properties to its possible role as a processing nuclease is discussed.
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Ribosomes Regulate the Stability and Action of the Exoribonuclease RNase R
TL;DR: A novel regulatory mechanism affecting RNase R, a 3′ to 5′ exoribonuclease able to act on essentially all RNAs including those with extensive secondary structure is described, indicating a previously unknown role for ribosomes in cellular homeostasis.