M
Myka L. Estes
Researcher at Indiana University
Publications - 8
Citations - 614
Myka L. Estes is an academic researcher from Indiana University. The author has contributed to research in topics: Endothelial stem cell & CD34. The author has an hindex of 6, co-authored 8 publications receiving 569 citations. Previous affiliations of Myka L. Estes include Indiana University – Purdue University Indianapolis.
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Journal ArticleDOI
Flow Cytometric Identification and Functional Characterization of Immature and Mature Circulating Endothelial Cells
TL;DR: Two populations of circulating endothelial cells, including the functionally characterized ECFC, are now identifiable in human cord blood and peripheral blood by PFC.
Journal ArticleDOI
In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony forming cell numbers and function
David A. Ingram,Izlin Z. Lien,Laura E. Mead,Myka L. Estes,Daniel N. Prater,Ethel Derr-Yellin,Linda A. DiMeglio,Laura S. Haneline +7 more
TL;DR: It is demonstrated that hyperglycemia or exposure to a diabetic intrauterine environment diminishes neonatal ECFC function both in vitro and in vivo, providing potential mechanistic insights into the long-term cardiovascular complications observed in newborns of diabetic pregnancies.
Journal ArticleDOI
Identification of endothelial cells and progenitor cell subsets in human peripheral blood.
Myka L. Estes,Myka L. Estes,Julie A. Mund,Julie A. Mund,David A. Ingram,David A. Ingram,Jamie Case,Jamie Case +7 more
TL;DR: A reproducible PFC protocol is provided to identify a rare circulating endothelial colony‐forming cell (ECFC) with proliferative potential, along with a population of circulating progenitor cells (CPCs) in which the ratio analysis distinguishes between healthy and disease populations.
Journal ArticleDOI
Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential
Myka L. Estes,Julie A. Mund,Julie A. Mund,Laura E. Mead,Daniel N. Prater,Shanbao Cai,Haiyan Wang,Karen E. Pollok,Karen E. Pollok,Michael P. Murphy,Caroline S. T. An,Edward F. Srour,David A. Ingram,Jamie Case +13 more
TL;DR: A PFC protocol validated via in vitro and in vivo analyses can be used to interrogate the roles of human hematopoietic elements in the growth and maintenance of the vasculature.
Journal ArticleDOI
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
Elisabeth A. Lasater,Fang Li,Waylan K. Bessler,Myka L. Estes,Sasidhar Vemula,Cynthia M. Hingtgen,Mary C. Dinauer,Reuben Kapur,Simon J. Conway,David A. Ingram +9 more
TL;DR: Genetic and cellular evidence of vascular inflammation in NF1 patients and Nf1+/- mice is provided and a framework for understanding the pathogenesis of NF1 vasculopathy and potential therapeutic and diagnostic interventions is provided.