N. Magnus Hjelm

TL;DR: In this paper, a real-time quantitative PCR assay was developed to measure the concentration of fetal DNA in maternal plasma and serum, and the results showed that fetal DNA is present in high concentrations in maternal placenta, reaching a mean of 25.4 genome equivalents/ml (range 3.3-69.4) in early pregnancy and 292.2 genome equivalents /ml(range 76.9-769) in late pregnancy.

TL;DR: The rapid turnover of circulating DNA suggests that plasma DNA analysis may be less susceptible to false-positive results, which result from carryover from previous pregnancies, than is the detection of fetal cells in maternal blood; also, rapid turnover may be useful for the monitoring of feto-maternal events with rapid dynamics.

TL;DR: Results suggest that quantitative analysis of plasma EBV DNA may be a useful clinical and research tool in the screening and monitoring of NPC patients.

TL;DR: The results suggest that circulating liver tumor DNA may be detected using tumor-associated DNA methylation changes, which may have implications for the noninvasive detection of a wide variety of cancers.

TL;DR: Plasma DNA is increased after trauma and may be a potentially valuable prognostic marker for these patients with adverse outcomes, including acute lung injury, acute respiratory distress syndrome, and death.