N
Na Li
Researcher at Beihang University
Publications - 123
Citations - 2937
Na Li is an academic researcher from Beihang University. The author has contributed to research in topics: Medicine & Hyperspectral imaging. The author has an hindex of 27, co-authored 95 publications receiving 2165 citations. Previous affiliations of Na Li include Capital Medical University & Leiden University Medical Center.
Papers
More filters
Journal ArticleDOI
Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types
Vincent van Unen,Thomas Höllt,Thomas Höllt,Nicola Pezzotti,Na Li,Marcel J. T. Reinders,Elmar Eisemann,Frits Koning,Anna Vilanova,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt +10 more
TL;DR: Hierarchical Stochastic Neighbor Embedding (HSNE) is introduced, a method for analysis of mass cytometry data that can handle very large datasets and allows their intuitive and hierarchical exploration.
Journal ArticleDOI
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care
Ella R. Thompson,Simone M Rowley,Na Li,Simone McInerny,Lisa Devereux,Michelle W. Wong-Brown,Alison H. Trainer,Gillian Mitchell,Rodney J. Scott,Paul A. James,Ian G. Campbell +10 more
TL;DR: The frequency of mutations in most breast cancer panel genes among individuals selected for possible hereditary breast cancer is low and, in many cases, similar or even lower than that observed among cancer-free population controls.
Journal ArticleDOI
miR-9 Regulation of BRCA1 and Ovarian Cancer Sensitivity to Cisplatin and PARP Inhibition
Chaoyang Sun,Na Li,Zongyuan Yang,Bo Zhou,Yang He,Danhui Weng,Yong Fang,Peng Wu,Pingbo Chen,Xiao-kui Yang,Ding Ma,Jianfeng Zhou,Gang Chen +12 more
TL;DR: In this article, a bioinformatics-driven microRNA (miR) library screening was used to identify miRs that regulate BRCA1 expression in sporadic ovarian cancer, and the effects of miR-9 on cisplatin and PARP inhibitor sensitivity were measured in ovarian cancer cells and C13* xenograft mice.
Journal ArticleDOI
Memory CD4(+) T cells are generated in the human fetal intestine
Na Li,Vincent van Unen,Tamim Abdelaal,Tamim Abdelaal,Nannan Guo,Sofya A. Kasatskaya,Sofya A. Kasatskaya,Kristin Ladell,James E. McLaren,Evgeny S. Egorov,Mark Izraelson,Susana M. Chuva de Sousa Lopes,Thomas Höllt,Thomas Höllt,Olga V. Britanova,Jeroen Eggermont,Noel F C C de Miranda,Dmitriy M. Chudakov,David Price,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Frits Koning +21 more
TL;DR: Functional assays combined with mass cytometry, single-cell RNA sequencing and high-throughput T cell antigen receptor (TCR) sequencing provide evidence for the generation of memory-like CD4+ T cells in the human fetal intestine that is consistent with exposure to foreign antigens.
Journal ArticleDOI
Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets.
Vincent van Unen,Na Li,Ilse Molendijk,Mine Temurhan,Thomas Höllt,Andrea E. van der Meulen-de Jong,Hein W. Verspaget,M. Luisa Mearin,Chris J. J. Mulder,Jeroen van Bergen,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Frits Koning +12 more
TL;DR: High-dimensional mass cytometry is used to generate a system-wide view of the human mucosal immune system and indicates that an integrated high-dimensional analysis of the entire immune system can identify immune subsets associated with the pathogenesis of complex intestinal disorders.