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Na-Yi Yuan Wu
Researcher at Central South University
Publications - 27
Citations - 162
Na-Yi Yuan Wu is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 6 publications receiving 53 citations.
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Utility of gene methylation analysis, cytological examination, and HPV-16/18 genotyping in triage of high-risk human papilloma virus-positive women.
Yan Tian,Na-Yi Yuan Wu,Yu-Ligh Liou,Ching-Tung Yeh,Lanqin Cao,Ya-Nan Kang,Huei-Jen Wang,Yichen Li,Tang-Yuan Chu,Wei Li,Xiang Liu,Yi Zhang,Hong-Hao Zhou,Yu Zhang +13 more
TL;DR: A dual methylation test for PAX1/ZNF582 and testing for ZNF582 methylation demonstrated 100% association of methylation with pathology results, indicating carcinoma in situ or squamous cell carcinoma, which could reduce the number of patients referred for colposcopic examination by 31.3% compared with cytology, and thus provide a feasible follow-up solution in regions where colposcopy is not readily available.
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Natural history of ovarian high-grade serous carcinoma from time effects of ovulation inhibition and progesterone clearance of p53-defective lesions.
TL;DR: The natural history of ovarian high-grade serous carcinoma begins at the first ovulation and spans for more than 30 years, taking 10 years from the normal tubal epithelium to the “p53 signature” status, another 15 years to progesterone receptor negative serous tubal intraepithelial carcinoma, and a final 5+ years to high-grades carcinoma.
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The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity
Jingguan Lin,Longzheng Xia,Linda Oyang,Jiaxin Liang,Shiming Tan,Na-Yi Yuan Wu,Pin Yi,Qing Pan,Shanshan Rao,Yaqian Han,Yanyan Tang,Min Su,Xia Luo,Yiqing Yang,Xiaohui Chen,Lixia Yang,Yujuan Zhou,Qianjin Liao +17 more
TL;DR: In this paper , the effect of POU domain class 2 transcription factor 1 (POU2F1) on metabolic reprogramming in colon cancer was explored, and the effects of altered POU 2F1 expression on proliferation, glucose metabolism and oxaliplatin sensitivity of colon cancer cells were tested.
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TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α degradation
Yong-Chang Chen,Lu Liu,Longzheng Xia,Na-Yi Yuan Wu,Ying Wang,He Li,Xue Chen,Xiaoye Zhang,Zhao-Yi Liu,Miaochen Zhu,Qianjin Liao,Jing Wang +11 more
TL;DR: In this paper , the effects of TRPM7 silencing on transcriptome profile, glucose uptake, lactic acid production, extracellular acidification rate (ECAR), oxygen consumption rate (OCR), intracellular ROS and ATP levels, and NAD+/NADH ratios in ovarian cancer cells were examined.
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Integrative Bioinformatics Approaches to Screen Potential Prognostic Immune-Related Genes and Drugs in the Cervical Cancer Microenvironment.
Zitong Zhao,Zitong Zhao,Jigang Li,He Li,Na-Yi Yuan Wu,Peilin Ou-Yang,Shan Liu,Jingting Cai,Jing Wang +8 more
TL;DR: A comprehensive understanding of prognostic genes within the TIME may provide new strategies for cervical cancer treatment and potential drugs for key prognostics DEGs were predicted using DrugBank.