N
Nader Perroud
Researcher at University of Geneva
Publications - 189
Citations - 7410
Nader Perroud is an academic researcher from University of Geneva. The author has contributed to research in topics: Borderline personality disorder & Bipolar disorder. The author has an hindex of 43, co-authored 162 publications receiving 6287 citations. Previous affiliations of Nader Perroud include King's College London & Dalhousie University.
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Journal ArticleDOI
Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs.
TL;DR: A role of BDNF and NT-3 neurotrophin, in the pathophysiology of suicidal behavior is supported, which may implicate the hippocampus and the PFC but not the entorhinal cortex, and both neurotrophins are mediators of psychotropic drugs.
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Increased methylation of glucocorticoid receptor gene ( NR3C1 ) in adults with a history of childhood maltreatment: a link with the severity and type of trauma
Nader Perroud,Ariane Paoloni-Giacobino,Paco Boris Prada,Emilie Olié,Emilie Olié,Annick Salzmann,Rosetta Nicastro,Sébastien Guillaume,Sébastien Guillaume,Dominique Mouthon,Christelle Stouder,Karen Dieben,Philippe Huguelet,Philippe Courtet,Philippe Courtet,Alain Malafosse +15 more
TL;DR: It is suggested that early life events may permanently impact on the HPA axis though epigenetic modifications of the NR3C1, a mechanism by which childhood maltreatment may lead to adulthood psychopathology.
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Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project
Rudolf Uher,Nader Perroud,Mandy Y.M. Ng,Joanna Hauser,Neven Henigsberg,Wolfgang Maier,Ole Mors,Anna Placentino,Marcella Rietschel,Daniel Souery,Tina Zagar,Piotr M. Czerski,Borut Jerman,Erik Roj Larsen,Thomas G. Schulze,Astrid Zobel,Sarah Cohen-Woods,Katrina Pirlo,Amy W. Butler,Pierandrea Muglia,Michael R. Barnes,Mark Lathrop,Anne Farmer,Gerome Breen,Katherine J. Aitchison,Ian W. Craig,Cathryn M. Lewis,Peter McGuffin +27 more
TL;DR: The results suggest that efficacy of antidepressants may be predicted by genetic markers other than traditional candidates, and genome-wide studies, if properly replicated, may be important steps in the elucidation of the genetic basis of pharmacological response.
Journal ArticleDOI
Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene
Nader Perroud,Annick Salzmann,Paco Boris Prada,Rosetta Nicastro,M E Hoeppli,S Furrer,Stefano Ardu,Ivo Krejci,Félicien Karege,Alain Malafosse +9 more
TL;DR: A relationship between child maltreatment and higher DNA methylation of BDNF is found and the idea that these epigenetic marks may be changed through psychotherapeutic approaches and that these changes underline changes in cognitive functions is supported.
Journal ArticleDOI
Prevalence and heritability of compulsive hoarding: a twin study.
Alessandra C. Iervolino,Nader Perroud,Miguel A. Fullana,Michel Guipponi,Lynn Cherkas,David A. Collier,David Mataix-Cols +6 more
TL;DR: Compulsive hoarding is highly prevalent and heritable, at least in women, with nonshared environmental factors also likely to play an important role.