N
Nadia Naffakh
Researcher at Pasteur Institute
Publications - 107
Citations - 4478
Nadia Naffakh is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Influenza A virus & Virus. The author has an hindex of 34, co-authored 99 publications receiving 4028 citations. Previous affiliations of Nadia Naffakh include Sorbonne & Centre national de la recherche scientifique.
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Journal ArticleDOI
Influenza virus infection induces widespread alterations of host cell splicing
U. Ashraf,Clara Benoit-Pilven,Vincent Navratil,Cécile Ligneau,Guillaume Fournier,Sandie Munier,Odile Sismeiro,Jean-Yves Coppée,Vincent Lacroix,Nadia Naffakh +9 more
TL;DR: It is shown that IAV infection of human lung cells induces widespread alterations of cellular splicing, with an overall increase in exon inclusion and decrease in intron retention and hijacking of RED by IAVs to promote splicing of the abundant viral NS1 mRNAs could partially divert RED from its target m RNAs.
Avis en réponse à la saisine 150519 - dossier C-NL-13-02. Paris, le 7 septembre 2015
Comité Scientifique Du Haut Conseil Des Biotechnologies,Claude Bagnis,Avner Bar-Hen,Avner Bar-Hen,Marie Anne Barny,Florence Bellivier,Philippe Berny,Yves Bertheau,Pascal Boireau,Thierry Brévault,Bruno Chauvel,Francois-Christophe Coleno,Denis Couvet,Elie Dassa,Hubert de Verneuil,Nathalie Eychenne,Claudine Franche,Philippe Guerche,Joël Guillemain,Guillermina Hernandez Raquet,André Jestin,Bernard Klonjkowski,Marc Lavielle,Valérie Le Corre,Olivier Lemaire,Didier Lereclus,Rémi Maximilien,Eliane F. Meurs,Cédric Moreau de Bellaing,Nadia Naffakh,Didier Nègre,Jean-Louis Noyer,Sergio Ochatt,Jean-Christophe Pages,Daniel Parzy,Catherine Regnault-Roger,Michel Renard,Patrick Saindrenan,Pascal Simonet,Marie-Bérengère Troadec,Bernard E. Vaissière,Jean Luc Vilotte +41 more
TL;DR: Le Haut Conseil des biotechnologies (HCB) a ete saisi le 20 mai 2015 par les autorites competentes francaises (le ministere de l’Agriculture, de l'Agroalimentaire et de la Foret) d'une demande d’avis relative au dossier C/NL/13/02 de demande de mise sur le marche de la lignee d'oeillets genetiquement modifies FLO-40685-1 a
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Continuous delivery of erythropoietin in mice using encapsulated genetically engineered cells lines
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Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
U. Ashraf,L. Tengo,L. Le Corre,G. Fournier,G. Fournier,G. Fournier,Patricia Busca,Andrew A. McCarthy,Rameix-Welti,Christine Gravier-Pelletier,Rob W.H. Ruigrok,Yves Jacob,Yves Jacob,Yves Jacob,Pierre-Olivier Vidalain,Nicolas Pietrancosta,Thibaut Crépin,Nadia Naffakh +17 more
TL;DR: The data demonstrate the potential of RED-SMU1 destabilizing molecules as an antiviral therapy that could be active against a wide range of influenza viruses and be less prone to drug resistance.
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Sensitivity of H5N1 influenza viruses to oseltamivir: an update
TL;DR: The factors that might limit the efficacy of oseltamivir treatment for human H5N1 infections are discussed, in addition to options for improving treatment efficacy and limiting the development of drug resistance.