N
Nagahiro Saijo
Researcher at AstraZeneca
Publications - 386
Citations - 31129
Nagahiro Saijo is an academic researcher from AstraZeneca. The author has contributed to research in topics: Lung cancer & Chemotherapy. The author has an hindex of 65, co-authored 386 publications receiving 28187 citations. Previous affiliations of Nagahiro Saijo include Harvard University.
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Journal ArticleDOI
In vitro antitumor effect of recombinant human tumor necrotizing factor on cultured human cancer cell lines and freshly isolated lung cancer cells by the human tumor clonogenic assay.
Yasutsuna Sasaki,Fumihiko Kanzawa,Hidenobu Takahashi,Yuka Matsushima,Hidehiko Nakano,Kazuhiko Nakagawa,Weon Seon Hong,Koichi Minato,Yasuhiro Fujiwara,Nagahiro Saijo +9 more
TL;DR: It can be concluded that rH-TNF has modest direct cytotoxic effect on lung cancer, and additional study against adenocarcinoma of the lung might be warranted.
Journal Article
Effect of peplomycin plus carbazilquinone and mitomycin on non-small cell carcinoma of the lung.
Nagahiro Saijo,Shimizu E,Kenji Eguchi,Shinkai T,Keigo Tominaga,Masahiko Shibuya,Shimabukuro Z,Niitani H,Akio Hoshi +8 more
TL;DR: It was concluded that the chemotherapeutic regimens that include PLM are only marginally effective against non-small cell carcinoma of the lung, with relatively frequent pulmonary fibrosis.
Journal ArticleDOI
Distant failure after treatment of postoperative locoregional recurrence of non-small cell lung cancer.
Katsuyuki Hotta,Ikuo Sekine,Kenji Suzuki,Haruhiko Kondo,Hisao Asamura,M. Sumi,Noboru Yamamoto,Hideo Kunitoh,Yuichiro Ohe,Tomoki Tamura,Tetsuro Kodama,Nagahiro Saijo,Ryousuke Tsuchiya +12 more
TL;DR: It was shown that local therapy for the locoregional recurrence had no significant impact on postrecurrent survival or distant failure-free survival, and systemic chemotherapy in addition to local therapy may be of benefit in this population.
Journal ArticleDOI
In vivo and in vitro effects of Nocardia rubra cell wall skeleton on natural killer activity in mice.
Nagahiro Saijo,Akira Ozaki,Yasuo Beppu,Nobuhiro Irimajiri,Masahiko Shibuya,Shimizu E,Takeo Takizawa,Takeshi Taniguchi,Akio Hoshi +8 more
TL;DR: The in vivo and in vitro effects of Nocardia rubra cell wall skeleton (N-CWS) on natural killer activity of spleen and peritoneal lymphocytes of C57BL/6 mice were studied.
Journal Article
Sister Chromatid Exchanges Induced in Human Lymphocytes by cis-Diamminedichloroplatinum(II)
Keijo Tominaga,Tetsu Shinkai,Nagahiro Saijo,Kenji Eguchi,Shimizu E,Yasutsuna Sasaki,Jiro Fujita,Takashi Nakajima +7 more
TL;DR: Pt(II) is a potent inducer of SCE in human lymphocytes in vivo and in vitro, and follow-up study of the long-term survivors who have been treated with this agent for cancer is necessary because of the possible occurrence of secondary neoplasms.