N
Nagahiro Saijo
Researcher at AstraZeneca
Publications - 386
Citations - 31129
Nagahiro Saijo is an academic researcher from AstraZeneca. The author has contributed to research in topics: Lung cancer & Chemotherapy. The author has an hindex of 65, co-authored 386 publications receiving 28187 citations. Previous affiliations of Nagahiro Saijo include Harvard University.
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Selection of surrogate marker genes in primary central nervous system lymphomas for radio-chemotherapy by DNA array analysis of gene expression profiles.
Ryuya Yamanaka,Shigeru Akutagawa,Fumiko Taguchi,Naoki Yajima,Naoto Tsuchiya,Takeo Uzuka,Ken Morii,Hideaki Takahashi,Ryuichi Tanaka,Nagahiro Saijo,Kazuto Nishio +10 more
TL;DR: Accumulation of data with respect to the expression profiles of PCNSL specimens, clinicopathological data, susceptibility to treatment, and outcome will provide information for identifying optimal therapeutic modalities for individual patients and novel therapeutic targets.
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Human Tumor Clonogenic Assay for Carcinoma of the Lung
Fumihiko Kanzawa,Yuka Matsushima,Anne W. Hamburger,Junichi Ishihara,Yasutsuna Sasaki,Shimizu E,Kenji Eguchi,Tetsu Shinkai,Nagahiro Saijo,Naoto Miyazawa +9 more
TL;DR: An improved method for disaggregation of solid tumors increased the yield of single cells and more than 10 anticancer drugs could be tested in 94 of 168 specimens, and cloning efficiencies varied markedly from specimen to specimen.
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New strategies for cancer therapy in the 21st century.
TL;DR: A large number of patients die from recurrent disease and the limitations of treatment in terms of effectiveness and tolerability have driven researchers to develop new strategies to reduce treatment-related toxicity and improve the survival rates of cancer patients.
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Reduction of pulmonary metastases of B16 melanoma by human recombinant interleukin 2 and lymphokine-activated killer cells in immunosuppressed C57BL/6 mice receiving anticancer agent.
Nagahiro Saijo,Akira Ozaki,Masanori Sakurai,Junichi Ishihara,Hidenobu Takahashi,Yasutsuna Sasaki,Akio Hoshi,Anne W. Hamburger +7 more
TL;DR: The administration of LAK cells and/or human rIL-2 restored the cytotoxicity of spleen lymphocytes against YAC-1 and syngeneic B- 16 melanoma cells in ACNU-treated mice, and these treatments partially suppressed the increased numbers of artificial pulmonary metastases of B-16 melanomacells.
Journal ArticleDOI
Cooperative group portfolio in locally advanced non-small-cell lung cancer: are we making progress?
Corey J. Langer,Heather A. Wakelee,Joan H. Schiller,Hak Choy,Frances A. Shepherd,Everett E. Vokes,Alex A. Adjei,Paul Baas,Nagahiro Saijo,David R. Gandara +9 more
TL;DR: This work explores the portfolio of clinical trials being conducted in locally advanced NSCLC by North American cooperative oncology groups as well as ongoing trials in Europe and Japan and focuses on radiation dose escalation using image-guided radiation therapy aswell as newer cytotoxic agents.