Nahid Fakhraei

TL;DR: The experimental results of the previous publications of oleuropein for NO and OH scavenging confirmed the presence of this unique active site in its molecular structure, but 2,2-diphenylpicrylhydrazyl (DPPH) cannot find this non-marginal active site and may not be a determinant assay for all antioxidant comparisons.

TL;DR: In this article, the molecular characteristics of Crocin (digentiobiosyl-8,8′-diapocarotene-8-8′)-8, 8′-oate; C44H64O24), naturally occurring carotenoid pigment compound, such as: the ionization potential (I), electron affinity (A), electronegativity (χ), electrophicility (ω), and hardness have been calculated using Density Functional Theory (DFT) approach with B3LYP/6-31G(d

TL;DR: New insights are found into the gut-brain communication during the development of colonic inflammation, which may ultimately lead to improved therapeutic strategies to combat behavior changes associated with gastrointestinal disorders.

TL;DR: Findings demonstrated, for the first time, a possible role for nitrergic and opioidergic systems in the aforementioned protective effect, and the extract probably exerted its impact increasing nitric oxide and opioid tones.

TL;DR: It is concluded that NO might be involved in spatial memory improvement by atorvastatin, as this effect is reversed by L-NAME and aminoguanidine in short-term memory acquisition.