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Nalini Mistry
Researcher at University of Leicester
Publications - 24
Citations - 1675
Nalini Mistry is an academic researcher from University of Leicester. The author has contributed to research in topics: DNA damage & Vitamin C. The author has an hindex of 15, co-authored 24 publications receiving 1615 citations. Previous affiliations of Nalini Mistry include Leicester Royal Infirmary & University Hospitals of Leicester NHS Trust.
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Journal ArticleDOI
Vitamin C exhibits pro-oxidant properties
Ian D. Podmore,Helen R. Griffiths,Karl E. Herbert,Nalini Mistry,Pratibha Mistry,Joseph Lunec +5 more
TL;DR: It is reported here that vitamin C administered as a dietary supplement to healthy humans exhibits a pro-oxidant, as well as an antioxidant, effect in vivo.
Journal ArticleDOI
Novel repair action of vitamin C upon in vivo oxidative DNA damage
Marcus S. Cooke,Mark D. Evans,Ian D. Podmore,Karl E. Herbert,Nalini Mistry,Pratibha Mistry,Peter T. Hickenbotham,Amina Hussieni,Helen R. Griffiths,Joseph Lunec +9 more
TL;DR: The kinetics of 8‐oxo‐2′‐deoxyguanosine removal and processing in vivo are illustrated, for the first time in humans, suggesting a role for vitamin C in the regulation of DNA repair enzymes and thereby demonstrating a non‐scavenging antioxidant effect.
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The effects of vitamin C supplementation on protein oxidation in healthy volunteers.
Julie L. Carty,Ruth J. Bevan,Helen L. Waller,Nalini Mistry,Marcus S. Cooke,Joseph Lunec,Helen R. Griffiths +6 more
TL;DR: Dietary vitamin C supplementation can reduce certain types of oxidative protein damage in subjects with low basal antioxidant, as well as eliminate any effect from seasonal variation in dietary antioxidant intake.
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Immunogenicity of DNA Damaged by Reactive Oxygen Species—Implications for Anti-DNA Antibodies in Lupus
TL;DR: Examination of immunogenicity in rabbits and the antigenicity of UVA, UVB, and UVC irradiated DNA for lupus anti-DNA antibodies suggests that ROS-DNA may be a factor in antigen-driven immune complex formation in SLE.
Journal ArticleDOI
Role of dietary antioxidants in the prevention of in vivo oxidative DNA damage.
TL;DR: Until further work has clarified whether dietary supplementation with antioxidants confers a reduced risk of cancer and the mechanism by which this effect is exerted, the recommendation for a diet rich in fruit and vegetables remains valid empirically.