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Nancy E. Everds
Researcher at Amgen
Publications - 50
Citations - 1975
Nancy E. Everds is an academic researcher from Amgen. The author has contributed to research in topics: Clinical pathology & Toxicity. The author has an hindex of 19, co-authored 50 publications receiving 1754 citations. Previous affiliations of Nancy E. Everds include Seattle Genetics & DuPont.
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Journal ArticleDOI
Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function.
Douglas Forrest,E Hanebuth,Richard J. Smeyne,Nancy E. Everds,C L Stewart,J M Wehner,T Curran +6 more
TL;DR: It is reported that targeted inactivation of the mouse TRbeta gene results in goitre and elevated levels of thyroid hormone, and this data define in vivo functions for TRbeta and indicate that specificity in T3 signalling is conferred by distinct receptor genes.
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Interpreting Stress Responses during Routine Toxicity Studies: A Review of the Biology, Impact, and Assessment
Nancy E. Everds,Paul W. Snyder,Keith Bailey,Brad Bolon,Dianne M. Creasy,George L. Foley,Thomas J. Rosol,Teresa S. Sellers +7 more
TL;DR: The historical and conventional methods used to characterize acute and chronic stress responses are described and the primary systems and parameters that regulate and/or are influenced by stress are reviewed, with an emphasis on parameters evaluated in toxicity studies.
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Selection and interpretation of clinical pathology indicators of hepatic injury in preclinical studies.
Laura Boone,Dennis J. Meyer,P. Cusick,D. Ennulat,A. Provencher Bolliger,Nancy E. Everds,V. Meador,G. Elliott,D. Honor,Denise Bounous,Holly Jordan +10 more
TL;DR: This position paper delineates the expert recommendations of the Regulatory Affairs Committee of the American Society for Veterinary Clinical Pathology for the use of preclinical, clinical pathology endpoints in assessment of the potential for drug-induced hepatic injury in animals and humans.
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Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO).
Scott E. Loveless,Carol Finlay,Nancy E. Everds,Steven R. Frame,Peter J. Gillies,John C. O'Connor,Charles R. Powley,Gerald L. Kennedy +7 more
TL;DR: In both rats and mice, the overall responses to the linear/branched and the linear forms of PFOA were similar, but the branched form appears to be less potent.
Journal ArticleDOI
Experimental animal urine collection: a review
TL;DR: A continuous refinement in the procedures for collecting urine from experimental animals will be the most efficient way of proceeding in obtaining pure urine specimens for obtaining reliable research data.