N
Naoichiro Yukawa
Researcher at Kyoto University
Publications - 55
Citations - 1590
Naoichiro Yukawa is an academic researcher from Kyoto University. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 19, co-authored 55 publications receiving 1401 citations. Previous affiliations of Naoichiro Yukawa include Wakayama Medical University.
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The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody
Ran Nakashima,Yoshitaka Imura,Shio Kobayashi,Naoichiro Yukawa,Hajime Yoshifuji,Takaki Nojima,Daisuke Kawabata,Koichiro Ohmura,Takashi Usui,Takao Fujii,Katsuya Okawa,Tsuneyo Mimori +11 more
TL;DR: The anti-CADM-140 antibody was shown to recognize IFN induced with helicase C domain protein 1 (IFIH1), also known as the melanoma differentiation-associated gene 5 (MDA5), which is one of the RIG-I-like receptors and plays a role in innate immune responses.
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Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
Yoshinaga Ito,Takashi Usui,Shio Kobayashi,Mikiko Iguchi-Hashimoto,Hiromu Ito,Hiroyuki Yoshitomi,Takashi Nakamura,Masakazu Shimizu,Daisuke Kawabata,Naoichiro Yukawa,Motomu Hashimoto,Noriko Sakaguchi,Shimon Sakaguchi,Hajime Yoshifuji,Takaki Nojima,Koichiro Ohmura,Takao Fujii,Tsuneyo Mimori +17 more
TL;DR: In this article, the authors investigated the involvement of interleukin-17 (IL-17)-producing γ/δ T cells in pathogenic roles in collagen-induced arthritis.
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A Clinical, Pathological, and Genetic Characterization of Methotrexate-associated Lymphoproliferative Disorders
Noriyuki Yamakawa,Masakazu Fujimoto,Daisuke Kawabata,Chikashi Terao,Momoko Nishikori,Ran Nakashima,Yoshitaka Imura,Naoichiro Yukawa,Hajime Yoshifuji,Koichiro Ohmura,Takao Fujii,Toshiyuki Kitano,Tadakazu Kondo,Kimiko Yurugi,Yasuo Miura,Taira Maekawa,Hiroh Saji,Akifumi Takaori-Kondo,Fumihiko Matsuda,Hironori Haga,Tsuneyo Mimori +20 more
TL;DR: It is demonstrated that patients in the EBVMCU, a specific clinical subgroup of MTX-LPD, had a better clinical outcome when MTX was withdrawn than did other patients with MTX -LPD.
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Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.
Masaki Katayama,Koichiro Ohmura,Naoichiro Yukawa,Chikashi Terao,Motomu Hashimoto,Hajime Yoshifuji,Daisuke Kawabata,Takao Fujii,Yoichiro Iwakura,Tsuneyo Mimori +9 more
TL;DR: Neutrophils are essential as a source of IL-17 in the effector phase of arthritis by using K/BxN serum-induced arthritis model, and stimulation of neutrophils with immune complex causedIL-17 secretion.
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Anti-U1 RNP antibodies in cerebrospinal fluid are associated with central neuropsychiatric manifestations in systemic lupus erythematosus and mixed connective tissue disease.
Takeshi Sato,Takao Fujii,Tomoko Yokoyama,Yoshimasa Fujita,Yoshitaka Imura,Naoichiro Yukawa,Daisuke Kawabata,Takaki Nojima,Koichiro Ohmura,Takashi Usui,Tsuneyo Mimori +10 more
TL;DR: The frequency of anti-U1 RNP antibodies in the CSF and the anti-RNP index are useful indicators of central NPSLE in anti- U1 R NP antibody-positive patients.