T
Takao Fujii
Researcher at Wakayama Medical University
Publications - 187
Citations - 4849
Takao Fujii is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 34, co-authored 180 publications receiving 4110 citations. Previous affiliations of Takao Fujii include Keio University & Kyoto University.
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Journal ArticleDOI
Efficacy of rituximab (Anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system
Mikiko Tokunaga,Kazuyoshi Saito,Daisuke Kawabata,Yoshitaka Imura,Takao Fujii,Shingo Nakayamada,Shizuyo Tsujimura,Masao Nawata,Shigeru Iwata,Taeko Azuma,Tsuneyo Mimori,Yoshiya Tanaka +11 more
TL;DR: Rituximab rapidly improved refractory NPSLE, as evident by resolution of various clinical signs and symptoms and improvement of radiographic findings, and the down regulation of functional molecules on B and T cells suggests that ritUXimab modulates the interaction of activated B andT cells through costimulatory molecules.
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The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody
Ran Nakashima,Yoshitaka Imura,Shio Kobayashi,Naoichiro Yukawa,Hajime Yoshifuji,Takaki Nojima,Daisuke Kawabata,Koichiro Ohmura,Takashi Usui,Takao Fujii,Katsuya Okawa,Tsuneyo Mimori +11 more
TL;DR: The anti-CADM-140 antibody was shown to recognize IFN induced with helicase C domain protein 1 (IFIH1), also known as the melanoma differentiation-associated gene 5 (MDA5), which is one of the RIG-I-like receptors and plays a role in innate immune responses.
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Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies.
Hajime Yoshifuji,Takao Fujii,Shio Kobayashi,Yoshitaka Imura,Yoshimasa Fujita,Daisuke Kawabata,Takashi Usui,Masao Tanaka,Sonoko Nagai,Hisanori Umehara,Tsuneyo Mimori +10 more
TL;DR: Screening of anti-ARS may be useful to predict late-onset myopathy in ILD-preceding patients and to predict the clinical course of ILD in PM/DM patients.
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Comprehensive microRNA Analysis Identifies miR-24 and miR-125a-5p as Plasma Biomarkers for Rheumatoid Arthritis.
Koichi Murata,Moritoshi Furu,Hiroyuki Yoshitomi,Masahiro Ishikawa,Hideyuki Shibuya,Motomu Hashimoto,Yoshitaka Imura,Takao Fujii,Hiromu Ito,Tsuneyo Mimori,Shuichi Matsuda +10 more
TL;DR: It is suggested that the plasma concentrations of miR-24 and mi-125a-5p, and ePRAM are potential diagnostic markers of RA even if patients were ACPA-negative.
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Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
Yoshinaga Ito,Takashi Usui,Shio Kobayashi,Mikiko Iguchi-Hashimoto,Hiromu Ito,Hiroyuki Yoshitomi,Takashi Nakamura,Masakazu Shimizu,Daisuke Kawabata,Naoichiro Yukawa,Motomu Hashimoto,Noriko Sakaguchi,Shimon Sakaguchi,Hajime Yoshifuji,Takaki Nojima,Koichiro Ohmura,Takao Fujii,Tsuneyo Mimori +17 more
TL;DR: In this article, the authors investigated the involvement of interleukin-17 (IL-17)-producing γ/δ T cells in pathogenic roles in collagen-induced arthritis.