N
Naoki Tanaka
Researcher at Shinshu University
Publications - 223
Citations - 7526
Naoki Tanaka is an academic researcher from Shinshu University. The author has contributed to research in topics: Steatosis & Fatty liver. The author has an hindex of 43, co-authored 209 publications receiving 6193 citations. Previous affiliations of Naoki Tanaka include National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease
Changtao Jiang,Changtao Jiang,Cen Xie,Fei Li,Limin Zhang,Robert G. Nichols,Kristopher W. Krausz,Jingwei Cai,Yunpeng Qi,Zhong-Ze Fang,Shogo Takahashi,Naoki Tanaka,Dhimant Desai,Shantu Amin,Istvan Albert,Andrew D. Patterson,Frank J. Gonzalez +16 more
TL;DR: It is demonstrated that inhibition of an intestinal FXR/ceramide axis mediates gut microbiota-associated NAFLD development, linking the microbiome, nuclear receptor signaling, andNAFLD.
Journal ArticleDOI
Removal of small colorectal polyps in anticoagulated patients: a prospective randomized comparison of cold snare and conventional polypectomy
TL;DR: Delayed bleeding requiring hemostasis occurred significantly less commonly after cold snare polypectomy than conventional polypectom despite continuation of anticoagulants.
Journal ArticleDOI
Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis.
TL;DR: Evaluating the efficacy and safety of EPA on 23 biopsy-proven NASH patients in a pilot trial found it to be safe and efficacious, largely due to its anti-inflammatory and antioxidative properties.
Journal ArticleDOI
Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.
Limin Zhang,Robert G. Nichols,Jared B. Correll,Iain A. Murray,Naoki Tanaka,Philip B. Smith,Troy D. Hubbard,Aswathy Sebastian,Istvan Albert,Emmanuel Hatzakis,Frank J. Gonzalez,Gary H. Perdew,Andrew D. Patterson +12 more
TL;DR: Findings provide new insights into the biochemical consequences of TCDF exposure involving the alteration of the gut microbiota, modulation of nuclear receptor signaling, and disruption of host metabolism.
Journal ArticleDOI
Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis
Naoki Tanaka,Tsutomu Matsubara,Kristopher W. Krausz,Andrew D. Patterson,Andrew D. Patterson,Frank J. Gonzalez +5 more
TL;DR: Phospholipid and bile acid metabolism is disrupted in NASH, likely due to enhanced hepatic inflammatory signaling.