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Nariaki Toita
Researcher at Hokkaido University
Publications - 23
Citations - 279
Nariaki Toita is an academic researcher from Hokkaido University. The author has contributed to research in topics: Medicine & Genetic enhancement. The author has an hindex of 9, co-authored 18 publications receiving 234 citations.
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Journal ArticleDOI
Epstein-Barr virus-associated B-cell lymphoma in a patient with DNA ligase IV (LIG4) syndrome
Nariaki Toita,Norikazu Hatano,Satoru Ono,Masafumi Yamada,Ryoji Kobayashi,Ichiro Kobayashi,Nobuaki Kawamura,Motohiko Okano,Akira Satoh,Atsuko Nakagawa,Koichi Ohshima,Masanobu Shindoh,Tsuyoshi Takami,Kunihiko Kobayashi,Tadashi Ariga +14 more
TL;DR: A 14-year-old Japanese girl with a progressing combined immunodeficiency had developed non-Hodgkin's diffuse large B cell lymphoma and her molecular analysis showed a compound heterozygote of novel mutations in the LIG4 gene, M249V substitution and a five nucleotides deletion from nucleotide position 1,270-1,274.
Journal ArticleDOI
Intrafamilial, Preferentially Mother-to-Child and Intraspousal, Helicobacter pylori Infection in Japan Determined by Mutilocus Sequence Typing and Random Amplified Polymorphic DNA Fingerprinting
Shin-ichi Yokota,Mutsuko Konno,Shin-ichi Fujiwara,Nariaki Toita,Michiko Takahashi,Soh Yamamoto,Noriko Ogasawara,Tsukasa Shiraishi +7 more
TL;DR: Whether multilocus sequence typing (MLST) was useful for analysis of intrafamilial infection of Helicobacter pylori was examined and the possibility of intraspousal infection was evaluated.
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Stem cell transplantation in primary immunodeficiency disease patients.
Tomonobu Sato,Ryoji Kobayashi,Nariaki Toita,Makoto Kaneda,Norikazu Hatano,Akihiro Iguchi,Nobuaki Kawamura,Tadashi Ariga +7 more
TL;DR: Stem cell transplantation can be curative for primary immunodeficiency diseases, but standardized protocols for each disease have not yet been established.
Journal ArticleDOI
Positive Relationship Between a Polymorphism in Helicobacter pylori Neutrophil‐Activating Protein A Gene and Iron‐Deficiency Anemia
TL;DR: This work has found that strains isolated from IDA patients showed higher levels of Fe ion uptake and Fe‐ion‐dependent rapid proliferation than those of strains derived from patients without IDA.
Journal ArticleDOI
Outcomes in two Japanese adenosine deaminase-deficiency patients treated by stem cell gene therapy with no cytoreductive conditioning.
Makoto Otsu,Masafumi Yamada,Satoru Nakajima,Miyuki Kida,Yoshihiro Maeyama,Norikazu Hatano,Nariaki Toita,Shunichiro Takezaki,Yuka Okura,Ryoji Kobayashi,Yoshinori Matsumoto,Osamu Tatsuzawa,F. Tsuchida,Shunichi Kato,Masanari Kitagawa,Junichi Mineno,Michael S. Hershfield,Pawan Bali,Fabio Candotti,Masafumi Onodera,Nobuaki Kawamura,Yukio Sakiyama,Tadashi Ariga +22 more
TL;DR: Treatment outcomes in two adenosine deaminase (ADA)-deficiency patients who received stem cell gene therapy (SCGT) with no cytoreductive conditioning provide insights into SCGT for ADA deficiency, and reiterate the importance of cytore ductive conditioning to ensure greater benefits from SCGT.