N
Narine Sarvazyan
Researcher at George Washington University
Publications - 93
Citations - 3144
Narine Sarvazyan is an academic researcher from George Washington University. The author has contributed to research in topics: Radiofrequency ablation & Hyperspectral imaging. The author has an hindex of 25, co-authored 91 publications receiving 2781 citations. Previous affiliations of Narine Sarvazyan include Texas Tech University Health Sciences Center & University of Toledo Medical Center.
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Journal ArticleDOI
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
Yuji Shiba,Sarah Fernandes,Wei-Zhong Zhu,Dominic Filice,Veronica Muskheli,Jonathan Kim,Nathan J. Palpant,Jay Gantz,Kara White Moyes,Hans Reinecke,Benjamin Van Biber,Todd F. Dardas,John L. Mignone,Atshushi Izawa,Ramy Hanna,Mohan N. Viswanathan,Joseph D. Gold,Michael I. Kotlikoff,Narine Sarvazyan,Matthew W. Kay,Charles E. Murry,Michael A. Laflamme +21 more
TL;DR: Injured hearts with hESC-CM grafts show improved mechanical function and a significantly reduced incidence of both spontaneous and induced ventricular tachycardia, providing support for the continued development of h ESC-based cardiac therapies for both mechanical and electrical repair.
Journal ArticleDOI
Anthracycline Cardiotoxicity: From Bench to Bedside
Luca Gianni,Eugene H. Herman,Steven E. Lipshultz,Giorgio Minotti,Narine Sarvazyan,Douglas B. Sawyer +5 more
TL;DR: The First International Workshop on Anthracycline Cardiotoxicity, held in fall 2006, focused on the state-of-the-art knowledge and discussed the research needed to address the cardiotoxicity of these drugs and is incorporated into the framework of a broader review of preclinical and clinical issues.
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Voltage-Gated Na+ Channel SCN5A Is a Key Regulator of a Gene Transcriptional Network That Controls Colon Cancer Invasion
Carrie D. House,Charles J. Vaske,Charles J. Vaske,Arnold M. Schwartz,Vincent Obias,Bryan Frank,Truong V. Luu,Narine Sarvazyan,Rosalyn B. Irby,Robert L. Strausberg,Tim G. Hales,Tim G. Hales,Joshua M. Stuart,Norman H. Lee +13 more
TL;DR: Probabilistic modeling of loss-of-function screens and microarray data established an unequivocal role of VGSC SCN5A as a high level regulator of a colon cancer invasion network, involving genes that encompass Wnt signaling, cell migration, ectoderm development, response to biotic stimulus, steroid metabolic process, and cell cycle control.
Journal ArticleDOI
Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes.
TL;DR: High-resolution fluorescence images obtained using laser-scanning confocal microscopy confirm an oxidative mechanism of doxorubicin cardiotoxicity and demonstrate the capability of a new technique to monitor intracellular oxidation in living cardiomyocytes.
Journal ArticleDOI
Localization of dichlorofluorescin in cardiac myocytes: implications for assessment of oxidative stress.
Luther Swift,Narine Sarvazyan +1 more
TL;DR: The study provides an information base essential for the interpretation and design of experiments with DCF as a marker of oxidative stress in cardiac muscle and reveals preferential localization of the probe in mitochondria.