N
Narito Morii
Researcher at Kyoto University
Publications - 108
Citations - 6974
Narito Morii is an academic researcher from Kyoto University. The author has contributed to research in topics: Angiotensin II & NPR2. The author has an hindex of 44, co-authored 108 publications receiving 6922 citations. Previous affiliations of Narito Morii include Tokyo Institute of Technology.
Papers
More filters
Journal ArticleDOI
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.
Toshimasa Ishizaki,Midori Maekawa,Kazuko Fujisawa,Katsuya Okawa,Akihiro Iwamatsu,Akiko Fujita,Naoki Watanabe,Y. Saito,Akira Kakizuka,Narito Morii,Shuh Narumiya +10 more
TL;DR: It is shown that p160 can associate physically and functionally with Rho both in vitro and in vivo, indicating that the small GTP‐binding protein Rho functions as a molecular switch in the formation of focal adhesions and stress fibers, cytokinesis and transcriptional activation.
Journal ArticleDOI
Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho
Go Watanabe,Y. Saito,Pascal Madaule,Toshimasa Ishizaki,Kazuko Fujisawa,Narito Morii,Hideyuki Mukai,Yoshitaka Ono,Akira Kakizuka,Shuh Narumiya +9 more
TL;DR: This study indicates that a serine-threonine protein kinase is a Rho effector and presents an amino acid sequence motif for binding to GTP-Rho that may be shared by a family of Rho target proteins.
Journal ArticleDOI
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain
Tim Reid,Tomoyuki Furuyashiki,Toshimasa Ishizaki,Go Watanabe,Naoki Watanabe,Kazuko Fujisawa,Narito Morii,Pascal Madaule,Shuh Narumiya +8 more
TL;DR: The N-terminal part of rhotekin, encoded by the initial cDNA and produced in bacteria as a glutathione S-transferase fusion protein, exhibited in vitro binding to 35S-labeled guanosine 5′-3-O-(thio)triphosphate-bound Rho, but not to Rac1 or Cdc42Hs in ligand overlay assays.
Journal ArticleDOI
Atrial natriuretic polypeptide: topographical distribution in the rat brain by radioimmunoassay and immunohistochemistry.
Mitsuhiro Kawata,Kazumasa Nakao,Narito Morii,Yoshiaki Kiso,Hiroshi Yamashita,Hiroo Imura,Yutaka Sano +6 more
TL;DR: An atlas of the distribution of the alpha-atrial natriuretic polypeptide-containing neuronal system in the rat brain is given and the groundwork for studying the influence of this new peptide on various brain functions is provided.
Journal ArticleDOI
A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs.
Issei Mabuchi,Yukihisa Hamaguchi,Hirotaka Fujimoto,Narito Morii,Masanori Mishima,Shuh Narumiya +5 more
TL;DR: Results strongly suggest that a rho-like, small GTP-binding protein is selectively involved in the organisation and maintenance of the contractile ring.