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Nasreen Z. Ehtesham

Researcher at Safdarjang Hospital

Publications -  129
Citations -  3417

Nasreen Z. Ehtesham is an academic researcher from Safdarjang Hospital. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 25, co-authored 113 publications receiving 2531 citations. Previous affiliations of Nasreen Z. Ehtesham include Centre for Cellular and Molecular Biology & International Centre for Genetic Engineering and Biotechnology.

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Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway.

TL;DR: Adding recombinant human resistin protein to macrophages resulted in enhanced secretion of pro-inflammatory cytokines, TNF-alpha and IL-12, similar to that obtained using 5 microg/ml lipopolysaccharide suggesting that the inflammatory action of resistin is independent of its conformation.
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Biofilms: Survival and defense strategy for pathogens.

TL;DR: The mechanisms used by microbes to develop and sustain biofilms, including the influence of the microbiota are highlighted, in a mini-review of currently available drugs and therapies against biofilm related infection.
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Differential effects of dietary saturated and trans-fatty acids on expression of genes associated with insulin sensitivity in rat adipose tissue.

TL;DR: The effects of SFAs on the aforementioned genes except PPARgamma could be extrapolated towards decreased insulin sensitivity, while only the alteration in the mRNA levels of PPargamma and resistin could be associated with insulin resistance in TFA-fed rats.
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The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications.

TL;DR: Comparisons of the mouse and human genomic fragments encoding the resistin gene report the presence of a PPAR/RXR heterodimer binding site within intron X (IntX-PPRE) which may possibly confer TZD responsiveness and oligonucleotides carrying the authentic PPar/R XR binding element present in differentiated 3T3-L1 adipocyte cells in an electrophoretic mobility shift assay.