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Natasha Taylor
Publications - 5
Citations - 314
Natasha Taylor is an academic researcher. The author has contributed to research in topics: Antibody & Neutralization. The author has an hindex of 4, co-authored 4 publications receiving 297 citations.
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Journal ArticleDOI
Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors
Elin S. Gray,Natasha Taylor,Diane Wycuff,Penny L. Moore,Georgia D. Tomaras,Constantinos Kurt Wibmer,Adrian Puren,Allan C. deCamp,Peter B. Gilbert,Blake Wood,David C. Montefiori,James M. Binley,George M. Shaw,Barton F. Haynes,John R. Mascola,Lynn Morris +15 more
TL;DR: This study suggests that more than one epitope on the envelope glycoprotein is involved in the cross-reactive neutralization elicited during natural HIV-1 infection, and that polyreactive antibodies are possibly involved in this phenomenon.
Journal ArticleDOI
Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression.
Isaac A. Choge,Tonie Cilliers,Polly R. Walker,Natasha Taylor,Mary Phoswa,Tammy Meyers,Johannes Viljoen,Avy Violari,Glenda Gray,Penny L. Moore,Maria Papathanosopoulos,Lynn Morris +11 more
TL;DR: This cross-sectional study shows that HIV-1 subtype C viruses from both rapid- and slow-progressing perinatally infected children used predominantly CCR5.
Journal ArticleDOI
Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies
Cecilia Rademeyer,Penny L. Moore,Natasha Taylor,Darren P. Martin,Isaac A. Choge,Elin S. Gray,Haynes W. Sheppard,Clive M. Gray,Lynn Morris,Carolyn Williamson +9 more
TL;DR: It is indicated that that some structural features of envelope, such as shorter variable loops, may facilitate the elicitation of cross-reactive neutralizing antibodies in natural infections and provide some insights into design features of an envelope immunogen aimed at inducingneutralizing antibodies.
Posted ContentDOI
Correlates of protection against SARS-CoV-2 Omicron variant and anti-spike antibody responses after a third/booster vaccination or breakthrough infection in the UK general population
J. Wei,P. Matthews,Nicole Stoesser,John N Newton,Ian Diamond,Ruth Studley,Natasha Taylor,John I. Bell,Jeremy Farrar,B Marsden,Jaison B. Kolenchery,Sarah Hoosdally,Yvonne Jones,Dave Stuart,D Crook,Tim E. A. Peto,A. Walker,Koen B. Pouwels,David W Eyre +18 more
TL;DR: In this paper , the authors investigated correlates of protection against Omicron BA.4/5 infections and anti-spike IgG antibody trajectories after a third/booster vaccination or breakthrough infection following second vaccination in 154,149 adults from the United Kingdom general population.
Journal ArticleDOI
High specificity of V3 serotyping among human immunodeficiency virus type-1 subtype C infected patients with varying disease status and viral phenotype.
TL;DR: The assay was able to identify HIV‐1 subtype C infection with a high level of sensitivity (94%) irrespective of the stage of disease and therefore provides a valuable resource for the large‐scale epidemiological monitoring of the spread of HIV‐ 1 subtypes in South Africa.