N
Nathan Rabinovitch
Researcher at University of Colorado Denver
Publications - 57
Citations - 1396
Nathan Rabinovitch is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Asthma & Leukotriene E4. The author has an hindex of 23, co-authored 51 publications receiving 1302 citations. Previous affiliations of Nathan Rabinovitch include National Jewish Health & University of British Columbia.
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Journal ArticleDOI
The Failure of STAT6-deficient Mice to Develop Airway Eosinophilia and Airway Hyperresponsiveness Is Overcome by Interleukin-5
Adrian Tomkinson,Arihiko Kanehiro,Nathan Rabinovitch,Anthony Joetham,Grzegorz Cieslewicz,Erwin W. Gelfand +5 more
TL;DR: Critically, it is shown that IL-5 alone can reconstitute airway eosinophilia and AHR in sensitized and challenged STAT6-/- mice, emphasizing the essential nature of the IL-4-dependent signaling of T cells to the Th2 phenotype and secretion of IL- 5, resulting in the airway Eosinophile and A HR.
Journal ArticleDOI
Importance of the personal endotoxin cloud in school-age children with asthma.
Nathan Rabinovitch,Andrew H. Liu,Lening Zhang,Charles Rodes,K.K. Foarde,Steven J. Dutton,James Murphy,Erwin W. Gelfand +7 more
TL;DR: Findings demonstrate the importance of using personal monitoring to both measure and correlate endotoxin exposure with asthma severity, and suggest exposures derived from sources in close proximity to the children's personal activities might be better correlated with disease severity.
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Particulate levels are associated with early asthma worsening in children with persistent disease.
TL;DR: In this paper, the association among ambient fine particulate, bronchodilator use, and urinary leukotriene E4 levels was assessed in children with persistent disease.
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Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma.
Nathan Rabinovitch,Nora J. Graber,Vernon M. Chinchilli,Christine A. Sorkness,Robert S. Zeiger,Robert C. Strunk,Leonard B. Bacharier,Fernando D. Martinez,Stanley J. Szefler +8 more
TL;DR: Children with LTE(4)/FE(NO) ratios at or above the 75th percentile were likely (P < .05) to be younger and female and exhibit lower levels of atopic markers and methacholine reactivity.
Journal ArticleDOI
Urinary leukotriene E4.
TL;DR: Urinary LTE4 measurements can be used as sensitive biomarkers of exposure to asthma triggers, such as air pollution and viral infections and the potential of using urinary LTE4 concentrations as predictors of asthma control and markers of susceptibility to treatment with leukotriene receptor antagonists is suggested.