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Ned R. Siegel
Researcher at Monsanto
Publications - 42
Citations - 3275
Ned R. Siegel is an academic researcher from Monsanto. The author has contributed to research in topics: Peptide sequence & Amino acid. The author has an hindex of 23, co-authored 42 publications receiving 3254 citations. Previous affiliations of Ned R. Siegel include Technion – Israel Institute of Technology.
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Journal ArticleDOI
Engineering herbicide tolerance in transgenic plants.
Dilip M. Shah,Robert B. Horsch,Harry J. Klee,Ganesh M. Kishore,Jill Winter,Nilgun E. Tumer,Cathy M. Hironaka,Patricia R. Sanders,Charles S. Gasser,Serdar Aykent,Ned R. Siegel,Stephen G. Rogers,Robert T. Fraley +12 more
TL;DR: Transformed petunia cells as well as regenerated transgenic plants were tolerant to glyphosate, and a chimeric EPSP synthase gene was constructed with the use of the cauliflower mosaic virus 35S promoter to attain high level expression.
Journal ArticleDOI
Purification and sequence analysis of bioactive atrial peptides (atriopeptins)
Mark G. Currie,David M. Geller,Barbara R. Cole,Ned R. Siegel,Kam F. Fok,Steven Paul Adams,Shad R. Eubanks,Gerald R. Galluppi,Philip Needleman +8 more
TL;DR: Both peptides appear to be derived from a common high molecular weight precursor (designated atriopeptigen); their biological selectivity and potency may be determined by the site of carboxyl terminal cleavage.
Journal ArticleDOI
Ser-Leu-Arg-Arg-atriopeptin III: the major circulating form of atrial peptide.
David S. Schwartz,David M. Geller,Pamela T. Manning,Ned R. Siegel,Kam F. Fok,Christine E. Smith,Philip Needleman +6 more
TL;DR: Fractionation of plasma atriopeptin immunoreactivity by reverse-phase high-performance liquid chromatography showed that the major portion consists of two species of low molecular weight peptides in a ratio of 10 to 1, and both peaks exhibited potent vasorelaxant activity, suggesting the presence of the carboxyl terminal Phe-Arg sequence of atRIopeptin in each species.
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Identification of an allatostatin from adult Diploptera punctata.
TL;DR: A peptide (allatostatin) causing strong and rapid inhibition of juvenile hormone synthesis in vitro by corpora allata from reproductively active females has been isolated from brain/retrocerebral complexes of the cockroach Diploptera punctata.
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A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: purification and N-terminal amino acid sequence.
Peter G. Milner,Yue-Sheng Li,Ruth M. Hoffman,Charles M. Kodner,Ned R. Siegel,Thomas F. Deuel +5 more
TL;DR: Hparin-binding growth factor-8 was as active as acidic fibroblast growth factor (aFGF) and slightly less active than bFGF in the mouse NIH 3T3 fibro Blast mitogenic assay system with an intrinsic specific activity of 5000 dpm/ng under standard assay conditions.