N
Nicholas Madian
Researcher at National Institutes of Health
Publications - 5
Citations - 106
Nicholas Madian is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Sensation & Nociception. The author has an hindex of 2, co-authored 4 publications receiving 77 citations.
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Journal ArticleDOI
Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates
Kendall Mitchell,Brian D. Bates,Jason M. Keller,Matthew Lopez,Lindsey Scholl,Julia Navarro,Nicholas Madian,Gal Haspel,Michael I. Nemenov,Michael J. Iadarola +9 more
TL;DR: Behavioral recovery following peripheral RTX treatment is linked to regeneration of TRPV1-expressing Adelta and C-fibers and sustained expression of molecular markers and Infrared laser stimulation is a potentially valuable tool for evaluating the behavioral role of Adelta fibers in pain and pain control.
Journal ArticleDOI
Innocuous pressure sensation requires A-type afferents but not functional ΡΙΕΖΟ2 channels in humans.
Laura K. Case,Jaquette Liljencrantz,Nicholas Madian,Aaron Necaise,Justin D. Tubbs,Micaela V. McCall,Megan Bradson,Marcin Szczot,Mark H. Pitcher,Nima Ghitani,Eleni Frangos,Jonathan Cole,Diana Bharucha-Goebel,Dimah Saade,Tracy Ogata,Sandra Donkervoort,A. Reghan Foley,Carsten G. Bönnemann,Håkan Olausson,M. Catherine Bushnell,Alexander T. Chesler +20 more
TL;DR: In this article, the authors used quantitative sensory evaluations of patients with rare sensory disorders, as well as nerve blocks in typical individuals, to probe the neural and genetic mechanisms for detecting nonpainful pressure.
Journal ArticleDOI
Aβ-CT Affective Touch: Touch Pleasantness Ratings for Gentle Stroking and Deep Pressure Exhibit Dependence on A-Fibers
Laura K. Case,Nicholas Madian,Micaela V. McCall,Megan Bradson,Jaquette Liljencrantz,Benjamin Goldstein,Vince J Alasha,Marisa S Zimmerman +7 more
TL;DR: For example, the authors showed that when mechanoreceptive A-fiber function is greatly diminished, the perceived intensity and pleasantness of both gentle stroking and deep pressure are nearly abolished.
Posted ContentDOI
Do we really understand the role of the prefrontal cortex in placebo analgesia
Eleni Frangos,Nicholas Madian,Binquan Wang,Megan Bradson,John L. Gracely,Emily A. Richards,Luana Colloca,Petra Schweinhardt,M.C. Bushnell,Marta Ceko +9 more
TL;DR: In this paper, the same subjects were examined during a conditioning procedure, in which expectancy of pain relief was high, and noxious heat was applied to a leg region treated with an ''analgesic'' cream and another treated with a ''moisturizing'' cream.