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Nick Bryan
Researcher at University of Pennsylvania
Publications - 20
Citations - 981
Nick Bryan is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Hyperintensity & Digit symbol substitution test. The author has an hindex of 9, co-authored 20 publications receiving 759 citations. Previous affiliations of Nick Bryan include University of Texas at Austin.
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Journal ArticleDOI
White matter hyperintensities and imaging patterns of brain ageing in the general population
Mohamad Habes,Mohamad Habes,Guray Erus,Jon B. Toledo,Tianhao Zhang,Nick Bryan,Lenore J. Launer,Yves Rosseel,Deborah Janowitz,Jimit Doshi,Sandra Van der Auwera,Bettina von Sarnowski,K Hegenscheid,Norbert Hosten,Georg Homuth,Henry Völzke,Ulf Schminke,Wolfgang Hoffmann,Hans J. Grabe,Christos Davatzikos +19 more
TL;DR: The hypothesis that white matter hyperintensities contribute to patterns of brain atrophy found in beyond-normal brain ageing in the general population is supported.
Journal ArticleDOI
Cerebral MRI findings and cognitive functioning The Atherosclerosis Risk in Communities Study
Thomas H. Mosley,David S. Knopman,Diane J. Catellier,Nick Bryan,Richard G. Hutchinson,C. A. Grothues,Aaron R. Folsom,Lawton S. Cooper,Gregory L. Burke,Duanping Liao,Moyses Szklo +10 more
TL;DR: Common changes in brain morphology are associated with diminished cognitive functioning in middle-aged and young-elderly individuals.
Journal ArticleDOI
White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy
Mohamad Habes,Aristeidis Sotiras,Guray Erus,Jon B. Toledo,Deborah Janowitz,David A. Wolk,Haochang Shou,Nick Bryan,Jimit Doshi,Henry Völzke,Ulf Schminke,Wolfgang Hoffmann,Wolfgang Hoffmann,Susan M. Resnick,Hans J. Grabe,Hans J. Grabe,Christos Davatzikos +16 more
TL;DR: The hypothesis that the appearance of WMH follows age and disease-dependent regional distribution patterns, potentially influenced by differential underlying pathophysiologic mechanisms, and possibly with a differential link to vascular and neurodegenerative changes is supported.
Journal ArticleDOI
Postmenopausal hormone therapy and subclinical cerebrovascular disease: the WHIMS-MRI Study
Laura H. Coker,Patricia E. Hogan,Nick Bryan,Lew Kuller,Karen L. Margolis,Kerstin Bettermann,Robert B. Wallace,Zhiqiang Lao,R. Freeman,Marcia L. Stefanick,Sally A. Shumaker +10 more
TL;DR: Increased lesion volumes were significantly related to age, smoking, history of cardiovascular disease, hypertension, lower post-trial global cognition scores, and increased incident cases of on- or post- trial mild cognitive impairment or probable dementia.
Journal ArticleDOI
Cardiorespiratory fitness and cognitive function in middle age: The CARDIA Study
Na Zhu,David R. Jacobs,Pamela J. Schreiner,Kristine Yaffe,Nick Bryan,Lenore J. Launer,Rachel A. Whitmer,Stephen Sidney,Ellen W. Demerath,William Thomas,Claude Bouchard,Ka He,Jared P. Reis,Barbara Sternfeld +13 more
TL;DR: In this article, the authors investigated whether greater cardiorespiratory fitness (CRF) is associated with better cognitive function 25 years later, and found that better verbal memory and faster psychomotor speed at ages 43 to 55 years were clearly associated with a better CRF 25 years earlier.