M
Marcia L. Stefanick
Researcher at Stanford University
Publications - 504
Citations - 71848
Marcia L. Stefanick is an academic researcher from Stanford University. The author has contributed to research in topics: Women's Health Initiative & Breast cancer. The author has an hindex of 101, co-authored 469 publications receiving 65741 citations. Previous affiliations of Marcia L. Stefanick include University of California, Irvine & Oregon Health & Science University.
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Journal ArticleDOI
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
Jacques E. Rossouw,Garnet L. Anderson,Ross L. Prentice,Andrea Z. LaCroix,Charles Kooperberg,Marcia L. Stefanick,Rebecca D. Jackson,Shirley A.A. Beresford,Barbara V. Howard,Karen C. Johnson,Jane Morley Kotchen,Judith K. Ockene +11 more
TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial
Garnet L. Anderson,Marian C. Limacher,Annlouise R. Assaf,Tamsen Bassford,Shirley A.A. Beresford,Henry R. Black,Denise E. Bonds,Robert L. Brunner,Robert G. Brzyski,Bette J. Caan,Rowan T. Chlebowski,J. David Curb,Margery Gass,Jennifer Hays,Gerardo Heiss,Susan L. Hendrix,Barbara V. Howard,Judith Hsia,F. Allan Hubbell,Rebecca D. Jackson,Karen C. Johnson,Howard L. Judd,Jane Morley Kotchen,Lewis H. Kuller,Andrea Z. LaCroix,Dorothy S. Lane,Robert Langer,Norman L. Lasser,Cora E. Lewis,JoAnn E. Manson,Karen L. Margolis,Judith K. Ockene,Mary Jo O'Sullivan,Lawrence S. Phillips,Ross L. Prentice,Cheryl Ritenbaugh,John A Robbins,Jacques E. Rossouw,Gloria E. Sarto,Marcia L. Stefanick,Linda Van Horn,Jean Wactawski-Wende,Robert B. Wallace,Sylvia Wassertheil-Smoller +43 more
TL;DR: The use of conjugated equine estrogen (CEE) increases the risk of stroke, decreases therisk of hip fracture, and does not affect CHD incidence in postmenopausal women with prior hysterectomy over an average of 6.8 years, indicating no overall benefit.
Journal ArticleDOI
Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
Valery T. Miller,John C. LaRosa,Vanessa M. Barnabei,Craig M. Kessler,Ginny Levin,Ann Smith-Roth,Margaret Griffin,Diane B. Stoy,Trudy L. Bush,Howard A. Zacur,David A. Foster,Jean Anderson,Alice McKenzie,Susan C. Miller,Peter D. Wood,Marcia L. Stefanick,Robert Marcus,Allison Akana,W. Leroy Heinrichs,Charlene Kirchner,Katherine A. O'Hanlan,Melissa Ruyle,Mary A. Sheehan,Howard L. Judd,Gail A. Greendale,Richard Bayalos,Kathy Lozano,Kathy Kawakami,Elizabeth Barrett-Connor,Robert Langer,Donna Kritz-Silverstein,Mary Lou Carrion-Petersen,Carmela Cavero,Helmut G. Schrott,Susan R. Johnson,Deborah A. Feddersen,Denise L. Krutzfeldt,Jo Ann Benda,Carl J. Pauerstein,Jose Trabal,Robert S. Schenken,Michael P. Stern,Mercedes Rodriguez-Sifuentes,Carann Easton,H B Wells,Mark A. Espeland,George Howard,Robert Byington,Claudine Legault,Sally A. Shumaker,Patricia E. Hogan,Don Hire,Carol Wasilauskas,Margaret K. James,Kathy Lane,Tim Terrell,Stephanie Reece,June J Pierce,Mary Snow,Susan Anthony,Irma Mebane-Sims,Paula T. Einhorn,Sally Hunsberger,Myron A. Waclawiw,Ken Lippel,Diane L. Lucas,Joel Verter,Sherry Jackson,Joseph Kelaghan,Jeffrey M. Perlman,Pam Wolf,Joan McGowan,Stephen Gordon,Stephen Heyse,Judith E. Fradkin,Sherry Sherman,Lot B. Page,Ann Sorenson,Barbara S. Hulka,Baruch A. Brody,Ronald T. Burkman,Robert P. Heaney,Ronald M. Krauss,Harold Roberts,Janet Wittes,Lawrence Riggs,Richard Moss,John J. Albers,Santica M. Marcovina,S. Edwin Fineberg,Russell P. Tracy,Maria J. Merino,Robert E. Scully,Virginia A. LiVolsi,Gerald Kessler +94 more
TL;DR: Estrogen alone or in combination with a progestin improves lipoproteins and lowers fibrinogen levels without detectable effects on postchallenge insulin or blood pressure and in women with a uterus, CEE with cyclic MP has the most favorable effect on HDL-C and no excess risk of endometrial hyperplasia.
Journal ArticleDOI
Calcium plus vitamin D supplementation and the risk of fractures.
Rebecca D. Jackson,Andrea Z. LaCroix,Margery Gass,Robert B. Wallace,John A Robbins,Cora E. Lewis,Tamsen Bassford,Shirley A.A. Beresford,Henry R. Black,Patricia L. Blanchette,Denise E. Bonds,Robert L. Brunner,Robert G. Brzyski,Bette J. Caan,Jane A. Cauley,Rowan T. Chlebowski,Steven R. Cummings,Iris A. Granek,Jennifer Hays,Gerardo Heiss,Susan L. Hendrix,Barbara V. Howard,Judith Hsia,F. Allan Hubbell,Karen C. Johnson,Howard L. Judd,Jane Morley Kotchen,Lewis H. Kuller,Robert Langer,Norman L. Lasser,Marian C. Limacher,Shari E. Ludlam,JoAnn E. Manson,Karen L. Margolis,Joan McGowan,Judith K. Ockene,Mary Jo O'Sullivan,Lawrence S. Phillips,Ross L. Prentice,Gloria E. Sarto,Marcia L. Stefanick,Linda Van Horn,Jean Wactawski-Wende,Evelyn P Whitlock,Garnet L. Anderson,Annlouise R. Assaf,David H. Barad +46 more
TL;DR: Among healthy postmenopausal women, calcium with vitamin D supplementation resulted in a small but significant improvement in hip bone density, did not significantly reduce hip fracture, and increased the risk of kidney stones.
Journal ArticleDOI
Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women: The Women's Health Initiative Randomized Trial
Rowan T. Chlebowski,Susan L. Hendrix,Robert Langer,Marcia L. Stefanick,Margery Gass,Dorothy S. Lane,Rebecca J. Rodabough,Mary Ann Gilligan,Michele G. Cyr,Cynthia A. Thomson,Janardan D. Khandekar,Helen Petrovitch,Anne McTiernan +12 more
TL;DR: Relatively short-term combined estrogen plus progestin use increases incident breast cancers, which are diagnosed at a more advanced stage compared with placebo use, and also substantially increases the percentage of women with abnormal mammograms, a pattern which continued for the study duration.