N
Nicola Hawe
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 3
Citations - 1132
Nicola Hawe is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Gene & Hox gene. The author has an hindex of 3, co-authored 3 publications receiving 1093 citations.
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Journal ArticleDOI
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
Bihui H. Ye,Giorgio Cattoretti,Qiong Shen,Jiandong Zhang,Nicola Hawe,Rick De Waard,Cynthia C. Leung,Mahyar Nouri-Shirazi,Attilio Orazi,R. S. K. Chaganti,Paul B. Rothman,Alan M. Stall,Pier Paolo Pandolfi,Riccardo Dalla-Favera +13 more
TL;DR: BCL-6 functions as a transcriptional switch that controls germinal centre formation and may also modulate specific T-cell-mediated responses and develop an inflammatory response in multiple organs typical of a Th2-mediated hyperimmune response.
Journal ArticleDOI
Plzf regulates limb and axial skeletal patterning
TL;DR: It is shown that Plzf is essential for patterning of the limb and axial skeleton and acts as a regulator of Hox gene expression and is a mediator of anterior-to-posterior (AP) patterning in both the axial and appendicular skeleton.
Journal ArticleDOI
Gene Rearrangements in the Molecular Pathogenesis of Acute Promyelocytic Leukemia
Sundeep Kalantry,Laurent Delva,Mirella Gaboli,Domenica Gandini,Marco Giorgio,Nicola Hawe,Li Zhen He,Daniela Peruzzi,Roberta Rivi,Carla Tribioli,Zhugang Wang,Hui Zhang,Pier Paolo Pandolfi +12 more
TL;DR: The functional analysis of the various fusion proteins, as well as RARα partners, is revealing striking common features beneath a misleading structural heterogeneity which unravels a possible unifying molecular mechanism towards APL leukemogenesis.