N
Nicolaas de Jonge
Researcher at Utrecht University
Publications - 97
Citations - 3676
Nicolaas de Jonge is an academic researcher from Utrecht University. The author has contributed to research in topics: Heart failure & Heart transplantation. The author has an hindex of 28, co-authored 90 publications receiving 2972 citations. Previous affiliations of Nicolaas de Jonge include University of Groningen & University Medical Center Utrecht.
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Journal ArticleDOI
Advanced heart failure : a position statement of the Heart Failure Association of the European Society of Cardiology
María G. Crespo-Leiro,Marco Metra,Lars H. Lund,Davor Milicic,Maria Rosa Costanzo,Gerasimos Filippatos,Finn Gustafsson,Steven Tsui,Eduardo Barge-Caballero,Nicolaas de Jonge,Maria Frigerio,Righab Hamdan,Tal Hasin,Martin Hülsmann,Sanem Nalbantgil,Luciano Potena,Johann Bauersachs,A. Gkouziouta,Arjang Ruhparwar,Arsen D. Ristić,Ewa Straburzyńska-Migaj,Theresa McDonagh,Petar M. Seferović,Frank Ruschitzka +23 more
TL;DR: There is an urgent need to develop evidence‐based treatment algorithms to prolong life when possible and in accordance with patient preferences, increase life quality, and reduce the burden of hospitalization in this vulnerable patient population.
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2019 EACTS Expert Consensus on long-term mechanical circulatory support
Evgenij Potapov,Christiaan F J Antonides,María G. Crespo-Leiro,Alain Combes,G. Färber,Margaret M. Hannan,Marian Kukucka,Nicolaas de Jonge,Antonio Loforte,Lars Lund,Paul Mohacsi,Michiel Morshuis,Ivan Netuka,Mustafa Özbaran,Federico Pappalardo,Anna Mara Scandroglio,Martin Schweiger,Steven Tsui,Daniel Zimpfer,Fin Gustafsson +19 more
TL;DR: The evidence for the complete management from patient selection to end-of-life care is carefully reviewed with the aim of guiding clinicians in optimizing management of patients considered for or supported by an LT-MCS device.
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Management of chronic heart failure guided by individual N-terminal pro-B-type natriuretic peptide targets: results of the PRIMA (Can PRo-brain-natriuretic peptide guided therapy of chronic heart failure IMprove heart fAilure morbidity and mortality?) study.
Luc W. Eurlings,Petra E. van Pol,Wouter E.M. Kok,Sandra van Wijk,Cara L. B. Lodewijks-van der Bolt,A. H. M. M. Balk,Dirk J. Lok,Harry J.G.M. Crijns,Dave J. W. van Kraaij,Nicolaas de Jonge,Joan G. Meeder,Martin H. Prins,Yigal M. Pinto +12 more
TL;DR: Serial NT-proBNP measurement and targeting to an individual NT- ProBNP value did result in advanced detection of HF-related events and importantly influenced HF-therapy, but failed to provide significant clinical improvement in terms of mortality and morbidity.
Journal ArticleDOI
Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support
Sjoukje I. Lok,Bjorn Winkens,Roel Goldschmeding,Ankie J. P. van Geffen,Fay M.A. Nous,Joyce van Kuik,Petra van der Weide,C. Klöpping,J. Hans Kirkels,Jaap R. Lahpor,Pieter A. Doevendans,Nicolaas de Jonge,Roel A. de Weger +12 more
TL;DR: The aim was to study GDF‐15 in patients with a non‐ischaemic dilated cardiomyopathy (DCM) during LVAD support, which provides unloading of the left ventricle, resulting in partial reverse remodelling.
Journal ArticleDOI
Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy
Maartje Noorman,Sara Hakim,Elise L. Kessler,Judith A. Groeneweg,Moniek G.P.J. Cox,Angeliki Asimaki,Harold V.M. van Rijen,Leonie van Stuijvenberg,Halina Chkourko,Marcel A.G. van der Heyden,Marc A. Vos,Nicolaas de Jonge,Jasper J. van der Smagt,Dennis Dooijes,Aryan Vink,Roel A. de Weger,András Varró,Jacques M.T. de Bakker,Jeffrey E. Saffitz,Thomas J. Hund,Peter J. Mohler,Mario Delmar,Richard N.W. Hauer,Toon A.B. van Veen +23 more
TL;DR: A reduced immunoreactive signal of PKG, Cx43, and NaV1.5 at the intercalated disks can be observed in a large majority of the patients, which might contribute to arrhythmia vulnerability and serve as a new clinically relevant tool for risk assessment strategies.